This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/rcm.8874 This article is protected by copyright. All rights reserved. Samanthula Gananadhamu (Orcid ID: 0000-0002-6389-5994) Application of online liquid chromatography/quadrupole time-of-flight electrospray ionization tandem mass spectrometry for structural characterization of Linagliptin degradation products and related impurities Amrej Singh Yadav # , Divya Dornala # , Debasish Swain, Aishwarya Prabha, Gananadhamu Samanthula * National Institute of Pharmaceutical Education and Research [NIPER], Balanagar, Hyderabad # Authors with equal contribution. *Corresponding author: Dr S Gananadhamu Assistant Professor, Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research [NIPER], Hyderabad, Telangana, 500037, India. E-mail address: gana@niperhyd.ac.in ORCID number 0000-0002-6389-5994