Volume 7 • Issue 2 • 1000154 J Nanomedine Biotherapeutic Discov, an open access journal ISSN: 2155-983X Mini Review Open Access Journal of Nanomedicine & Biotherapeutic Discovery J o u r n a l o f N a n o m e d i c i n e & B i o t h e r a p e u t i c D i s c o v e r y ISSN: 2155-983X Khan et al., J Nanomedine Biotherapeutic Discov 2017, 7:2 DOI: 10.4172/2155-983X.1000154 Keywords: Cancer; Biogenic synthesis; Medicinal plants; Nanomedicine Introduction In the past era of anticancer research, very few developments have been made with regard to the practical progress towards cancer therapy. Defciencies in the feld to manage therapeutic moieties to achieve the preferred targets to cure cancer with minimal or no side efects [1]. Most importantly the acknowledgment that 1 and 10 parts per 100,000 of intravenously managed monoclonal antibodies come to their in vivo parenchymal focuses. Tere are two general, synergistic objectives that would be endeavoured to raise the efcacy of per dose of every therapeutic and secondly to provide the agents containing the therapeutic to overwhelmed biological barriers that retain it afer achieving its goal. A much better therapeutic framework would be focused against clusters of cells in the initial stages of cancer [2]. Such type of framework faces many difculties including the distinguishing proof of appropriate early markers of neoplastic infection and advancement afer some time the arrangement of such markers in the early recognizing protocols and screening; and advancement in the targeted delivery of many therapeutic agents, biomarkers and for coordinated capability of avoiding biophysical and biological obstructions [3]. Nanotechnology Nanotechnology is an emerging and multidisciplinary feld, which cover enormous and various range of procedures derived from felds like biology, chemistry, physics and engineering. Tese devices contain nano-vectors as a carrier for anticancer drugs. Formally the defnitions of nanotechnological devices feature the supplies that the device and its basic parts are man-made, and the range of the dimension must be in between 1-100 nm. In his defnition of nanotechnology, George Whitesides 11 places less stringent limitations on the exact dimensions, and characterizes the ‘right’ size in bio-nanotechnology in an operational manner in biology [4]. Nanotechnology conveys the possibility to be applied at the molecular level to control the matter of apprehension. Tis is a dynamic feld including biology, chemistry and physics of the nano scale objects. Remarkable research in nanotechnology has opened up new roads for drug delivery, treatment and diagnosis for cancer and many diseases other than cancer as well. Nanotechnology combined with metal nanoparticles has been efectively applied in various felds most importantly in biomedical sciences. Nanoparticles are considered suitable theranostic agents because of their shape, size and extraordinary optical and thermal characteristics [5]. Tese outstanding characteristics of metal based nanoparticles, which are due to a ratio of specifc size and elevated surface area to volume, make them perfect for many biological applications, including therapeutic diagnostics [6]. Synthesis of Nanoparticles via Biological, Chemical and Physical Methods Nanoparticles (NPs) synthesis can be carried out from various methods via physical, chemical and biological methods. Nonetheless, recent research shows that biological methods have assumed an awesome part in the synthesis of metal nanoparticles [7]. Micro- organisms such as fungi and bacteria can be used to synthesize nanoparticles, but on other hand the synthesis involving plants provides an eco-friendly and satisfactory approach since it is without the utilization of numerous costly, lethal and unsafe materials [8]. Among various biological resources, plants provide an ideal platform for the synthesis of NPs. Diferent advantages of plant derived nanoparticles contain rapid synthesis, improved stability and cost value. Furthermore, nanoparticles of numerous sizes and shapes can be produced using plants as compared with other organisms [9]. As compared to plants bacteria and fungi that require long incubation times for decrease of metal ions, the phytochemicals can do it rather rapidly and take out the need of costly and time consuming Bio-Synthesized Silver Nanoparticles Using Different Plant Extracts as Anti-Cancer Agent Khan Y *1 , Numan M 1 , Ali M 1 , Khali AT 2 , Ali T 3 , Abbas N 3 and Shinwari ZK 1,4 1 Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan 2 Qarshi University, Lahore, Pakistan 3 Kohat University of Science and Technology, Kohat, Pakistan 4 Pakistan Academy of Science, Islamabad, Pakistan Abstract With the development of the biogenic nanotechnologies, scientists are looking new ways to design novel strategies for the treatment and diagnosis of cancer. Advances in nanotechnology have attracted many researchers to the biogenic synthesis of metallic NPs because of its advantages like, simple, fast, one pot processes, economical and biocompatibility. Medicinal plants are selected to be the best reservoirs of diverse phytochemicals for the biogenic synthesis of silver nanoparticles (AgNPs). In this review, the top point discussed is mechanistic advances in the synthesis of AgNPs from medicinal plant extracts. We have discussed the recent improvements achieved in the use of biogenic AgNPs as cancer theranostic agents. Anticipating all of the challenges in the feld of cancer, we hope that biogenic AgNPs may become a potential cancer therapeutic and diagnostic agent in the near future. *Corresponding author: Yasmin Khan, Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan, Tel: +92 3416263258; E-mail: yasminkhanqau@gmail.com Received August 02, 2017; Accepted September 07, 2017; Published September 15, 2017 Citation: Khan Y, Numan M, Ali M, Khali AT, Ali T, et al. (2017) Bio-Synthesized Silver Nanoparticles Using Different Plant Extracts as Anti-Cancer Agent. J Nanomedine Biotherapeutic Discov 7: 154. doi: 10.4172/2155-983X.1000154 Copyright: © 2017 Khan Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.