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New blood pressure control goals,
more rational but facilitating
therapeutic inertia?
Carlos Escobar
a
, Vivencio Barrios
b
,
F. Javier Alonso-Moreno
c
, Jose Luis Llisterri
d
,
Gustavo C. Rodriguez-Roca
e
, Miguel Angel
Prieto
f
, on behalf of the Working Group of
Arterial Hypertension of the Spanish Society of
Primary Care Physicians (Group HTA/SEMERGEN)
and the PRESCAP 2010 investigators
N
ew guidelines for the management of arterial
hypertension have been recently published [1].
One of the most important novelties is the updated
blood pressure (BP) control targets according to the avail-
able evidence. Thus, a SBP less than 140 mmHg in general
hypertensive population, including those patients at higher
risk (i.e. diabetes, history of stroke, ischemic heart disease
or chronic kidney disease), has been recommended. More-
over, in elderly patients a SBP between 140 and 150 mmHg
has been recommended and in those less than 80 years old
a target of more than 140 mmHg may be considered in
selected patients. With regard to DBP goals, the guidelines
recommend a target of less than 90 mmHg in the general
population and less than 85 mmHg in diabetics [1].
What is the impact of these new targets in clinical
practice?
We recently published the evolution of BP control in
Spain in the last decade in the primary care setting using the
data from three cross-sectional studies (PRESCAP 2002,
PRESCAP 2006 and PRESCAP 2010) [2]. In this study, that
included a total of 36 235 patients (12 754 in PRESCAP 2002,
10 520 in PRESCAP 2006 and 12 961 in PRESCAP 2010),
the proportion of patients who achieved BP goals
(140/90 mmHg in the general population; <130/85 mmHg
in PRESCAP 2002 and <130/80 mmHg in PRESCAP 2006
and PRESCAP 2010 for patients with diabetes, chronic
kidney disease or cardiovascular disease) were 36.1, 41.4
and 46.3%, respectively (P < 0.0001). This was largely
associated with the higher use of combined therapy
(44, 56.6 and 63.6, respectively; P < 0.001) [2].
We have recalculated BP control rates of PRESCAP 2010
with the new BP targets. Thus, according to new 2013
recommendations, BP control improved in general popu-
lation from 46.3 to 60.8% (P < 0.0001). In diabetics, BP
control increased from 19.7 to 50.3%, P < 0.0001. In those
patients aged 80 years or older, the proportion of patients
who achieved BP targets increased from 40.8 to 77.2%
(P < 0.0001).
Although these data are encouraging, great efforts have
been made to improve the management of patients with
arterial hypertension, and this has been translated into a
progressive improvement of BP control rates [3]. In fact,
different strategies have been developed to improve patient
and physician awareness about the relevance of attaining
BP control, mainly through continuous medical education
[3]. For instance, different studies have reported that both,
general practitioners and specialist, frequently underesti-
mate the cardiovascular risk of hypertensive population in
daily clinical practice, mainly in very high-risk patients, and
this resulted in an increase of therapeutic inertia [4,5].
However, through this continuous medical education, in
which European guidelines have had a key role [6,7], BP
control rates have improved in parallel with the higher use
of combined therapy [2].
With all these data, one great concern about these new
BP goals may be that physicians may relax and worsen
therapeutic inertia. As a result, although these new BP goals
are evidence-based, medical societies and physicians
should be cautious in order to use antihypertensive therapy
when necessary to achieve BP targets.
ACKNOWLEDGEMENTS
Conflicts of interest
There are no conflicts of interest.
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Journal of Hypertension 2013, 31:2462–2465
a
Cardiology Department, Hospital La Paz,
b
Cardiology Department. Hospital Ramo ´ny
Cajal, Madrid,
c
Primary Care Center Sillerı´a, Toledo,
d
Primary Care Center Ingeniero
Joaquı´n Benlloch, Valencia,
e
Primary Care Center La Puebla de Montalban, Toledo and
f
Primary Care Center Vallobı´n-La Florida, Oviedo, Asturias, Spain
Correspondence to Carlos Escobar, Cardiology Department, Hospital La Paz, Madrid,
Spain. E-mail: escobar_cervantes_carlos@hotmail.com
J Hypertens 31:2462–2465 ß 2013 Wolters Kluwer Health | Lippincott Williams &
Wilkins.
DOI:10.1097/HJH.0000000000000002
2462 www.jhypertension.com Volume 31 Number 12 December 2013
Correspondence