Journal Pre-proof Morphological alterations caused by manual venom extraction on the main venom gland of Bothrops asper and Crotalus simus snakes (Serpentes: Viperidae): Long- term implications for antivenom production Sylvia Rodríguez-Abarca, Greivin Corrales, Danilo Chacón, Maricruz Guevara, Carolina Esquivel, Cynthia Arroyo, Aarón Gómez PII: S0041-0101(19)30725-1 DOI: https://doi.org/10.1016/j.toxicon.2019.10.242 Reference: TOXCON 6231 To appear in: Toxicon Received Date: 3 July 2019 Revised Date: 21 October 2019 Accepted Date: 30 October 2019 Please cite this article as: Rodríguez-Abarca, S., Corrales, G., Chacón, D., Guevara, M., Esquivel, C., Arroyo, C., Gómez, Aaró., Morphological alterations caused by manual venom extraction on the main venom gland of Bothrops asper and Crotalus simus snakes (Serpentes: Viperidae): Long-term implications for antivenom production, Toxicon (2019), doi: https://doi.org/10.1016/j.toxicon.2019.10.242. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier Ltd.