Abstract: Using a 96-hour static bioassay, authors looked at the effects of household Tide detergent on the blood parameters and energy metabolism of Asian snakehead fish (Channa punctata). The median 96-hour lethal dose (LC ) of HHD was 60.0 mg/L. The control group received a non- 50 detergent-treated standard meal. RBC count and haemoglobin considerably decreased; however, WBC count level noticeably increased at sublethal of dose 12.00 mg/L. There was a substantial up regulation of total protein. Organcholesterol and triglycerides rose, but total lipids decreased. Overall, the results showed that fish's biochemical and hematological parameters were significantly altered after exposure to detergent. Keywords: Acute toxicity, Biochemical parameters, Channa punctata, Detergent, Fish. International Journal of Biological Innovations http: //ijbi.org.in | http://www.gesa.org.in/journals.php https://doi.org/10.46505/IJBI.2023.5201 IJBI 5(2): 01-11 (2023) E-ISSN: 2582-1032 ALTERATION IN BIOCHEMICAL AND HAEMATOLOGICAL PARAMETERS ON EXPOSURE TO HOUSEHOLD DETERGENT (TIDE) OF THE ASIAN SNAKEHEAD FISH CHANNA PUNCTATA Preeti Singh and Rakesh Kumar Pandey* Department of Zoology Kamla Nehru Institute of Physical and Social Sciences, Sultanpur (U.P.), India *Corresponding author: rakeshzoology@gmail.com Article Info: Research Article Received 26.07.2023 Reviewed 15.09.2023 Accepted 08.10.2023 GESA GLOCAL ENVIRONMENT & SOCIAL ASSOCIATION Cite this article as: Singh P. and Pandey R.K. (2023). Alteration in biochemical and haematological parameters on exposure to household detergent (tide) of the Asian snakehead fish Channa punctata. International Journal of Biological Innovations. 5(2): 01-11. https://doi.org/10.46505/IJBI.2023.5201 This is an Open Access Article licensed under a Creative Commons license: Attribution 4.0 International (CC-BY). It allows unrestricted use of articles in any medium, reproduction and distribution by providing adequate credit to the author (s) and the source of publication. alkylbenzene sulfonate (ABS) (Abdel-Shafy et al. , 1988; Texter, 2001), and other ingredients such as foam stabilizers, colourants, bleaching agents, pigments, enzymes (proteases), water softeners (carbonates, silicates, poly-phosphates, and perborates), preservatives (sodium sulphate), and perfumes (Hauthal, 2016; Landeck et al., 2020). The exact composition of commercial products is proprietary. However, 15% surfactant, 30% poly-phosphate, and 10% silicate are the relative amounts of the ingredients, along with 20% sodium perborate and 20% sodium sulphate, and the rest are fluorescent pigments and enzymes. INTRODUCTION Detergents are derived from organic compounds that endure in the environment; however, their use is unavoidable due to their application as components of household cleaners and pesticides as well as the scattering of oil pollution in the ocean (Isyaku and Solomon, 2016). Because of their components, such as surfactant, which decreases the surface tensions of water, currently available detergents have a high cleaning capacity. These detergents are synthesized by using surfactant substances, including alkyl lauryl sulfonate (LAS), dodecylbenzene sulfonate (DBS), and