J. Bio. & Env. Sci. 2014 591 | Kasbparast et al RESEARCH PAPER OPEN ACCESS Effect of thiamine on blood glucose changes after maximal aerobic exercise in non-athlete university students male J.R. Mehdi Kasbparast * , Alireza Rahimi, Omid Yaghoobpour Yekani, Mehdi Rezaei Department of Sport Injury and Biomechanics, Faculty of Physical Education and Sport Sciences, Islamic Azad University, Karaj Branch, Alborz, Iran Article published on August 28, 2014 Key words: Blood glucose, non-athlete, maximal aerobic exercise, thiamine. Abstract This study is conducted with the aim of investigating the effect of vitamin B1 (Thiamine) on blood glucose changes. We observed that when the subjects received 300 mg thiamin /day, there was a lowering of blood glucose level after physical activity. Like the other B vitamins, thiamin is used to treat fatigue. High-dose thiamin supplementation may be helpful in preventing fatigue or accelerating recovery from exercise-induced fatigue. In this research 36 non-athlete university students male were selected with average 22.8±2.4, 174.19±4.67, 76.34 ± 5.36 and 42.36 ± 1.83 for age, height, weight and Vo2max respectively,(12 persons in each group).The subjects placed in three groups: Experimental Group A(EGA),Experimental Group B(EGB) and Control Group(CG).They have to exercise on treadmill before and after the thiamin consumption. First of all, blood glucose measured in three groups before exercise and then performed exercise on treadmill until exhaustion. Blood glucose changes in subjects measured by (GOD-PAP method) after the exercise (pre-test).The subject's consumed thiamin during 10 days (EGA 30 mg /day, EGB 300 mg/day and CG just placebo) Blood glucose changes measured in three groups like as pre-test, during and the end of the exercise on treadmill after 10 days (post-test). Our results indicates, that there is no changes in blood glucose in EGA (30 mg thiamin/day) and CG(placebo) but showed that blood glucose reduced in EGB (300 mg thiamin/day)(P>0.05). In fact, degree of exhaustion increased in EGB that they consumed 300 mg thiamin per day, and they could to do exercise for a long time. Like the other B vitamins, thiamin is used to treat fatigue. High-dose thiamin supplementation may be helpful in preventing fatigue or accelerating recovery from exercise-induced fatigue. * Corresponding Author: Kasbparast JR Mehdi  Mehdikasbparast@gmail.com Journal of Biodiversity and Environmental Sciences (JBES) ISSN: 2220-6663 (Print) 2222-3045 (Online) Vol. 5, No. 2, p. 591-597, 2014 http://www.innspub.net