Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved. Abstracts e209 Objective: Failing to reach blood pressure (BP) goals is a major problem in treat- ment of hypertension, causing a high socioeconomic burden, sequel morbidities and strongly increased mortality. Recent studies demonstrated that interventional decentralized telemonitoring (idTM ® ) can strongly improve BP management in hypertension including high risk patients. In the EDiMed-Project (efficiency anal- ysis of services in telemedicine) - supported by German Ministry for education and research - the cost-benefit ratio was analyzed and a positive socioeconomic impact was found. Design and method: This project aims at establishing a telemonitoring system that allows to extend this service to all European Excellence centers for hyperten- sion treatment and ultimately to all physicians treating hypertensive patients in Europe. For this effort, the unique software SciTIM ® providing highest standard of data security was developed for the register to allow: • Making idTM ® available to physicians and patients across Europe • Establishing telemedical standards for selected hypertensive indications (renal failure, pregnancy, juveniles) • Establishing a system for collections of high quality epidemiologic data from daily medical practice, ultimately extend beyond planned register • Establishing a digital interface for direct interaction between specialists and general practitioners based on patient data. Results: The register nucleus started with 8 ESH-centers in 2017. To integrate data directly from the data management systems the project has and will generate interfaces to the most commonly used medical data management systems. In addi- tion, the system provides an user interface to physicians, enabling to monitor their patient’s telemonitoring progress at the first time directly in their electronic health records enabling physicians to set individual patient limits and specific rules to pro-actively alert staff members via auto generated messages and daily reports. Conclusions: The EUSTAR consortium has establish a register based on needs of medical specialists under the aegis of the ESH and will roll out this register throughout Europe. A database was created that allows safe and standardized ex- change of data. The System include interfaces for data collection from medical measurement devices and be open for all possible providers and also for other data than the first two parameters blood pressure and body weight. PP.15.11 EVALUATION OF AFFECTIVE TEMPERAMENTS, DEPRESSION AND ANXIETY IN WHITE-COAT, WELL-TREATED AND RESISTANT HYPERTENSION AND IN HEALTHY CONTROLS J. Nemcsik 1 , B. Korosi 1 , D. Batta 1 , A. Laszlo 1 , A. Tabak 2 , D. Eorsi 1 , P. Torzsa 1 , O. Cseprekal 3 , A. Tisler 2 , Z.S. Nemcsik-Bencze 4 , X. Gonda 5 , Z. Rihmer 5 . 1 Department of Family Medicine, Semmelweis University, Budapest, Hungary, 2 First Department of Medicine, Semmelweis University, Budapest, Hungary, 3 Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, 4 Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary, 5 Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary Objective: Hypertension and mood disorders both increase the frequency of car- diovascular events. Affective temperaments are related to mood disorders, how- ever, less data are available about the relationship between affective temperaments and cardiovascular diseases. The aim of this study was to evaluate affective tem- perament scores, depression, anxiety, hemodynamic and arterial stiffness param- eters in healthy subjects (Cont), as well as in chronic, well-treated (Chr), chronic, resistant (Res) and white-coat (Wh) hypertensive patient populations. Design and method: In our study, 261 patients were included: 148 Chr, 29 Res, 17 Wh and 67 Cont subjects. The patients completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A), the Beck Depression Inventory (BDI) and the Hamilton Anxiety Scale (HAMA). Blood pressure was measured with a validated oscillometric device (Omron M3) and arterial stiffness was examined with tonometry (PulsePen). Results: Significant differences were found between the Cont, Chr, Res and Wh in brachial systolic blood pressure (121.44 ± 11.1, 131.66 ± 12.16, 151.1 ± 27.92, 136.31 ± 12.31 mmHg, respectively) and in pulse wave velocity (7.78 ± 1.39, 9.24 ± 2.19, 10.49 ± 2.76, 8.06 ± 1.61 m/s, resp.). In cyclothymic affective tem- perament scores we found significant differences between the Cont, Chr and Res groups (2(0–4), 3(1–5), 4(3–8), resp.) with the highest score in Res. In BDI scores also significant differences were found between Cont, Chr and Res (3(0–5), 5(2–9), 7(4–12.5), resp.), while in HAMA scores differences between Cont, Chr, Res and Wh (3(1–6), 5(2–9), 12 (6–19.5), 8(5–10.5), resp.) groups were found. Res group showed the worst BDI and HAMA profiles as well. Conclusions: Evaluation of affective temperaments might be helpful in identifica- tion of high-risk subgroups of hypertensive patients. However, prospective studies are required to confirm these observations. PP.15.12 MEDICUS, A MOBILE-BASED, A PATIENT- CENTERED APPROACH TO THE TRACKING, PREDICTION, AND PREVENTION OF HYPERTENSION AND CARDIOVASCULAR CONDITIONS N. Nehme 1 , B. Al Khatib 3 , B. Al Hakim 1,2 . 1 INiTS Universitäres Gründerservice, Vienna, Austria, 2 Paris&Co Incubator, Paris, France, 3 Damascus University, Damascus, Syria Objective: Lifestyle choices are critical contributors to the onset of hyperten- sion and related cardiovascular diseases (1, 2). However, patients and health prac- titioners are often confronted with the challenge of understanding and drawing meaningful conclusions from a large number of analysis reports such as blood tests, NGS data, etc. Design and method: Medicus is a healthcare platform that converts medical re- ports with their cryptic numbers and medical language into a visual experience with personalized easy-to-understand health insights and actionable recommenda- tions. Medicus is powered by a Medical Reasoning Engine that uses AI to encode medical knowledge. Results: One of our primary focuses at Medicus is hypertension and the heart health. We’re tracking biomarker changes in response to users’ profile (sex, age, ethnic origin), lifestyle habits (alcohol, smoking, diet type, activity, BMI), used medication, genetic predisposition or existing condition. To date, we cover and track vitals including blood pressure, heart rate (HR), temperature, along with other serum biomarkers such as hematological variables, lipids, glucose, renal, and liver markers. Such detailed data allows Medicus to give the user a custom- ized hypertension and cardiovascular health risk assessment while tracking users’ progression over time and linking it to lifestyle changes among others (3). In ad- dition to cardiac markers, new biomarkers will be added and analyzed via our algorithms, including blood pressure, and HR related variables such as resting, high resting, target, recovery HR, and HR variability in a variety of user profiles including healthy users, athletes, and hypertension or cardiac patients. By presenting our innovative platform to researchers and health practitioners, we aim to establish two-way research collaborations to improve our product and con- tribute to advancing the research, clinical and medical fields. Researchers can benefit from compliant patients data to support their studies and understand more the factors that affect hypertension and related cardiovascular conditions. Conclusions: In conclusion, Medicus’s goal is to change the way people under- stand and interact with their health by promoting the predict and prevent model (3). This personalized approach will significantly reduce the onset of conditions by focusing on measurable risk factors and driving positive behavioral change. PP.15.13 EFFECT OF RENAL DENERVATION ON BLOOD PRESSURE IN PATIENTS WITH RESISTANT HYPERTENSION AND TYPE 2 DIABETES MELLITUS AFTER A 2 YEARS FOLLOW-UP V. Mordovin, A. Falkovskaya, S. Pekarskiy, G. Semke, T. Ripp, I. Zyubanova, V. Lichikaki, A. Baev. Cardiology Research Institute, Tomsk NRMC, Tomsk, Russia Objective: Combination of the type 2 diabetes mellitus (T2DM) and resistant hypertension (RHTN) associated with very high cardiovascular risk. Renal dener- vation (RDN) is a new non-pharmaceutical approach for treating RHTN. The aim of this study was to evaluate long-term blood pressure (BP) lowering after RDN in patients with RHTN and T2DM.