Advance Publication Cover Page © 2018 The Chemical Society of Japan Advance Publication is a service for online publication of manuscripts prior to releasing fully edited, printed versions. Entire manuscripts and a portion of the graphical abstract can be released on the web as soon as the submission is accepted. Note that the Chemical Society of Japan bears no responsibility for issues resulting from the use of information taken from unedited, Advance Publication manuscripts. Insight into a structural demand for cold crystallization of small molecule. A case study for Schiff base compounds that exhibit prototropic tautomerization Katsunori Iwase,* Yasuhiro Toyama, Isao Yoshikawa, Yasuhisa Yamamura, Kazuya Saito, and Hirohiko Houjou* Advance Publication on the web February 22, 2018 doi:10.1246/bcsj.20170386