484 PURPOSE: Evidence has shown that cardiorespiratory fitness (CRF) and physical activity (PA) are associated with metabolic risk (MR) since young ages. The purpose of the present study was to analyze whether the association between CRF and MR was independent of sedentary behavior (SB) and moderate to vigorous PA (MVPA). METHODS: Participants were 413 Portuguese students (226 girls and 187 boys) aged 10-18 years old. Metabolic risk was defined from a clustering score including age-and-sex adjusted z- scores for waist circumference, HDL-Cholesterol, triglycerides, fasting glucose and mean arterial pressure. CRF was defined from the maximal oxygen uptake estimated from the 20m Shuttle Run Test. PA was objectively measured with accelerometers, during 7 consecutive days. Total PA was expressed as the average counts per minute. To determine the time spent in different PA intensities, the following counts intervals were considered: 0-99 for sedentary PA (SEDPA), 100-2295 for light PA (LIGPA), 2296-4011 for moderate PA and ≥4012 for vigorous PA. Tertiles were calculated for MR, CRF, SEDPA and MVPA. The first tertile of MR was set as the group at high metabolic risk (HMR), while the two remaining tertiles were defined as low metabolic risk. The first tertile of CRF and MVPA was defined as “low fit” and “less active”, while the remaining two groups were set as “fit” and “active”, respectively, for each variable. Logistic regression was carried out with HMR as the outcome and CRF, SEDPA and MVPA levels as the independent variables, with adjustments for age and sex. Significance level was set at 5%. RESULTS: In the logistic regression model, no associations were found between MR and SEDPA (OR=1.060; 95%CI=0.668-1.682; P=0.804) or MVPA (OR=1.305; 95%CI=0.820-2.077; P=0.261). On the other hand, those who were low fit had an increased risk for being at HMR (OR=4.543; 95%CI=2.904-7.106; P<0.001), independently of age, sex, SEDPA and MVPA levels. CONCLUSIONS: In terms of public health, it seems critical that interventions with young populations should be focused in the enhancement of cardiorespiratory fitness, beyond calls for changes in physical activity and sedentary behaviors, to reduce metabolic risk. Supported by FCT with grants PEst-OE/SAU/UI0617/2011 and PTDC/DTP-DES/1328/2012/FCT/FCOMP-01-0124-FEDER-028619 1786 Board #131 May 28, 2:00 PM - 3:30 PM Association of Body Composition and Physical Activity in Adolescents with Down Syndrome: Preliminary Analysis E. Andrew Pitchford, Alexandra Leptich, Dale A. Ulrich. University of Michigan, Ann Arbor, MI. (No relationships reported) Obesity is highly prevalent among persons with Down syndrome (DS). Low levels of moderate to vigorous physical activity (MVPA) likely contribute to this health disparity, but only low associative relationships have been found with body mass index (BMI). Due to characteristics of DS (e.g. short stature, unique fat distribution), BMI may not be precise enough to study this relationship. Three component analysis from dual-energy X-ray absportiometry (DXA) may assist with better understanding the association between body composition and MVPA. PURPOSE: To examine the association between total and regional fat mass from DXA and levels of MVPA from actigraphy. METHODS: Preliminary analyses were conducted with 6 adolescents (15±1.8yrs, 66% male) with DS who completed a DXA scan measuring total and regional (i.e. arms, legs, trunk) fat mass. BMI percentiles (CDC) from direct anthropometric measures were also calculated. Each participant wore a triaxial accelerometer for seven days at the waist. Puyau cut points, minimum wear time of 10 hours per day for 4 days, and 20 minute non-wear period criteria were used. Analyses include 1) descriptive statistics of DXA derived fat mass, BMI, and MVPA; and 2) bivariate correlations. RESULTS: Average percent body fat from DXA was 31% (±12%) with moderate to high body fatness detected in 66% of the sample. Average BMI was at the 89th (±11) percentile. Average MVPA was only 17.32 minutes per day. One participant met the guideline of 60 minutes of MVPA on a single day and 3 participants exceeded the 30 minute threshold on at least one day. The association between body fat and MVPA was stronger from DXA (r = -.794) than from BMI percentile (-.473). Among regional segments, associations were also high including the arms (- .871), legs (-.802), and trunk (-.782). Correlations did not reach significance (p<.05) due to sample size, but the r 2 values are meaningful. CONCLUSION: Excess fatness and low MVPA are common in DS. This preliminary analysis found a stronger association between MVPA and body fat from DXA than from BMI. DXA may provide a more precise measure of excess body fat in DS. Greater use of DXA may help to better understand factors influencing body composition. A more comprehensive analysis will be possible with a larger sample and typically developing control group; currently in progress. Supported by NIH F31 HD079227. 1787 Board #132 May 28, 2:00 PM - 3:30 PM Sports Participation Did Not Interfere with Mathematics Performance in Chinese Adolescents Jacky Ka-wai Chan, Stanley Sai-chuen Hui, FACSM. The Chinese University of Hong Kong, Hong Kong, Hong Kong. Email: jacky.sspe@cuhk.edu.hk (No relationships reported) Active physical activity (PA) participation is generally thought to affect the academic performance of students. However, this notion has not been verified, especially with respect to the Chinese population. PURPOSE: To examine the relationship between mathematics performance and the involvement of students in sports-type extra-curricular activity (SECA). METHODS: Ninety-two Chinese adolescents were recruited from a low-banding secondary school in Hong Kong and were followed for 24 months. Their SECA engagement and mathematics performance in the 9 th and 11 th grades were measured, and their academic scores were standardized into t-scores for comparison. The participants were split into two categories, namely, the SECA and non-SECA groups, based on a self-reported questionnaire. Health-related fitness profiles (body mass index (BMI), nine-minute run, one-minute sit-up, push-up, and sit-and-reach) were measured during the 11 th grade to evaluate potential associations with SECA participation. The fitness scores were standardized and compiled into composite fitness scores. RESULTS: ANCOVA (SES as covariate) revealed that the SECA group was physically fitter than the non-SECA group (F=6.273, p<0.01). Two-way repeated measures MANCOVA (grade x group, SES and fitness level as covariates) revealed that no interaction effects occurred between the SECA and non-SECA groups in terms of mathematics score (F=0.232, p=0.632). Nevertheless, the SECA group improved their mathematics performance more in the 11 th grade than in the 9 th grade (Δ=+0.452). The non-SECA group experienced a drop in performance (Δ=−0.211), although it was not statistically significant. Results from stepwise regression suggested that composite fitness scores significantly predicted mathematics performance (t=2.805, p<0.01) but not whether or not SECA participation. CONCLUSION: SECA participants displayed higher physical fitness level without compromising mathematics performance. The promising findings of this longitudinal study support sports activity for school-aged children. 1788 Board #133 May 28, 2:00 PM - 3:30 PM Obesity, Physical Activity And Health-related Physical Fitness In Korean Adolescents Aged 12-15 Years: The Asia-fit Study. Jong-Kook Song 1 , Soo-Yeon Park 2 , Stanley Sai Hui 3 , Hyun-Bae Kim 1 , Hyun-Chul Jung 1 , Hyo-Jung Kang 1 , Yong-Seok Shin 1 , Sung-Woo Jung 1 , Min-Hyung Kim 1 , Myong-Won Seo 1 , Bo-Ram Woo 1 , Seong-Kyun Lim 1 . 1 Kyung Hee University, Yongin, Korea, Republic of. 2 Yong In University, Yongin, Korea, Republic of. 3 The Chinese University of Hong Kong, Hong Kong, Hong Kong. Email: jksong@khu.ac.kr (No relationships reported) Childhood and adolescence obesity has increased dramatically over the past three decades. Due to this rapid prevalence increase and the associated health consequences, obesity is considered one of the most serious health challenges in Korea. PURPOSE: To investigate the current status of obesity, physical activity and health-related fitness level in Korean adolescents aged 12-15 years and to compare those variables according to the gender and age. METHODS: This was a cross-sectional and a multi-disciplinary collaborated study which has been implemented in eight Asian countries/cities. A total of 1,686 adolescents including 902 for male and 784 for female aged 12 to 15 years who are living at Seoul city in Korea participated in the study. Body height, mass and percent body fat were measured. Health-related fitness consisted of modified back saver sit-and-reach, hand grip strength, 1-min sit-ups and 15-m PACER. Physical activity (PA) and dietary intake were administered for all subjects. Copyright © 2015 by the American College of Sports Medicine. Unauthorized reproduction of this article is prohibited.