Progrès en urologie (2018) 28, 442—449 Disponible en ligne sur ScienceDirect www.sciencedirect.com ORIGINAL ARTICLE Predictors of biochemical recurrence after radical prostatectomy in an Afro-Caribbean population in Guadeloupe (French West Indies) Facteurs prédictifs de récidive biologique après prostatectomie radicale dans une population afro-caribéenne L. Brureau a,b,c,* , E. Emeville a,d , L. Multigner a,d , P. Blanchet a,b,c a Inserm, U1085, IRSET, 97145 Pointe-à-Pitre, Guadeloupe, France b Service d’urologie, University Hospital of Pointe-à-Pitre, 97159 Pointe-à-Pitre, France c Université de Rennes-1, 35700 Rennes, France d Université des Antilles, 97100 Pointe-à-Pitre, France Received 4 July 2017; accepted 28 March 2018 Available online 20 May 2018 KEYWORDS Afro-Caribbean; Biochemical recurrence; Predictive factors; Prostate cancer; Radical prostatectomy Summary Purpose. — Few studies have investigated predictive risk factors of biochemical recurrence (BCR) after radical prostatectomy (RP) in other than Caucasian and Asian populations. We aimed to identify pre- and post-operative predictors of BCR after RP in an Afro-Caribbean population in Guadeloupe (French West Indies). Patients and methods. — The study included 964 patients who underwent RP for clinically local- ized prostate cancer between April 1, 2000 and December 31, 2010 in the University Hospital of Guadeloupe. The hazard ratio (HR) and corresponding 95% confidence interval (CI) for single variable associations with BCR were calculated using the Cox proportional hazards regression. Multiple variable analyses for association with BCR were performed, including all variables that reached statistical significance (P value < 0.05) in univariate analysis. A backward selec- tion model was then applied with a P value ≥ 0.1 for retention in the final model. Sensitivity analysis was performed and restricted to patients with known values for all variables (complete case analysis). * Corresponding author. Service d’urologie, University Hospital of Pointe-à-Pitre, 97159 Pointe-à-Pitre, France. E-mail address: brureau laurent@yahoo.fr (L. Brureau). https://doi.org/10.1016/j.purol.2018.03.015 1166-7087/© 2018 Elsevier Masson SAS. All rights reserved.