Accepted Manuscript Synthesis and Biological Evaluation of Novel Doxorubicin-containing ASGP- R-targeted Drug-conjugates Yan A. Ivanenkov, Alexander G. Majouga, Rostislav A. Petrov, Stanislav A. Petrov, Sergey V. Kovalev, Svetlana Yu. Maklakova, Emil Yu. Yamansarov, Irina V. Saltykova, Ekaterina V. Deyneka, Gleb I. Filkov, Victor E. Kotelianski, Timofey S. Zatsepin, Elena K. Beloglazkina PII: S0960-894X(17)31164-2 DOI: https://doi.org/10.1016/j.bmcl.2017.12.004 Reference: BMCL 25460 To appear in: Bioorganic & Medicinal Chemistry Letters Received Date: 4 October 2017 Revised Date: 1 December 2017 Accepted Date: 2 December 2017 Please cite this article as: Ivanenkov, Y.A., Majouga, A.G., Petrov, R.A., Petrov, S.A., Kovalev, S.V., Maklakova, S.Y., Yamansarov, E.Y., Saltykova, I.V., Deyneka, E.V., Filkov, G.I., Kotelianski, V.E., Zatsepin, T.S., Beloglazkina, E.K., Synthesis and Biological Evaluation of Novel Doxorubicin-containing ASGP-R-targeted Drug- conjugates, Bioorganic & Medicinal Chemistry Letters (2017), doi: https://doi.org/10.1016/j.bmcl.2017.12.004 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.