_____________________________________________________________________________________________________ *Corresponding author: E-mail: nyams02@gmail.com; Asian Journal of Biotechnology and Bioresource Technology 7(4): 62-76, 2021; Article no.AJB2T.76811 ISSN: 2457-0125 Assessment of the Risk of Exposure of Côte D’ivoire Kola Nuts (Cola nitida Schott & Endl. to Pyrethrinoids and Oragnophosphorus Pesticides Deigna-Mockey Viviane 1 , Biego Godi Henri 1 , Nyamien Yves Bleouh 2* and Adama Coulibaly 3 1 Laboratory of Biochemistry and Food Science, Training and Research Unit of Biosciences, Felix Houphouët-Boigny University, 22 P.O.Box 582, Abidjan 22, Côte d’Ivoire. 2 Institute of Agropastoral Management, Peleforo Gon Coulibaly University, P.O.Box 1328, Korhogo, Côte d'Ivoire. 3 Training and Research Unit of Biological Sciences, Peleforo Gon Coulibaly University, P.O.Box 1328, Korhogo, Côte d'Ivoire. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/AJB2T/2021/v7i430110 Editor(s): (1) Dr. Fernando José Cebola Lidon, Universidade Nova de Lisboa, Portugal. Reviewers: (1) James Gimase, Kenya Agricultural and Livestock Research Organization, Kenya. (2) Awogbade, Adeyemi Lawrence, Federal college of Agriculture, Nigeria. Complete Peer review History, details of the editor(s), Reviewers and additional Reviewers are available here: https://www.sdiarticle5.com/review-history/76811 Received 14 September 2021 Accepted 18 November 2021 Published 27 November 2021 ABSTRACT Aims: The aim of this study was to assess the risk of exposure to pyrethrinoids and oragnophosphorus pesticides found in Côte d’Ivoire kola nuts. Study Design: Kola nuts samples were collected from farmers, collectors and urban stores in 3 regions (western, southwestern and eastern) and 2 big storage centers of Côte d’Ivoire. Place and Duration of Study: Health Department of Hydrology Health and Toxicology, Training and Research Unit of Pharmaceutical and Biological Sciences, Abidjan, Côte d’Ivoire, running 2017-2020. Methodology: Pyrethrinoids and organophosphorus residues were qualitatively and quantitatively determined using Liquid Chromatography-Tandem mass spectrometry Agilent 1290 Infinity II LC Original Research Article