ORIENTAL JOURNAL OF CHEMISTRY www.orientjchem.org An International Open Access, Peer Reviewed Research Journal ISSN: 0970-020 X CODEN: OJCHEG 2022, Vol. 38, No.(4): Pg. 822-839 This is an Open Access article licensed under a Creative Commons license: Attribution 4.0 International (CC- BY). Published by Oriental Scientifc Publishing Company © 2018 Pteridine a Colored Heterocycle and Its Anticancer activity: (An Overview) NEIL B. PANCHAL 1 * and VIPUL M. VAgHELA 2 1 Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Piparia, Waghodia, Vadodara, Gujarat, India. 2 Department of Pharmaceutical Chemistry, A. R. college of pharmacy & G. H. Patel Institute of Pharmacy, Vallabh Vidyanagar, Anand, Gujarat, India. *Corresponding author E-mail: neil.dop@sumandeepvidyapeethdu.edu.in, nbp9171@gmail.com http://dx.doi.org/10.13005/ojc/380402 (Received: May 04, 2022; Accepted: August 20, 2022) ABSTRACT The objective of this work is to provide an overview of the numerous pharmacological features that are associated with the pteridine molecule. Pteridines are nitrogen-containing heterocyclic compounds that are well-known and noteworthy. Their chemical formula is C 6 H 4 N 4 . In recent years, pteridine's various potential uses in the feld of medicinal chemistry research have garnered signifcant attention. In the expanding feld of intensive study, Pteridine is regarded as a privileged scaffold, and the alteration created with diverse substituents around the centroid opened the way for researchers to deal with it at ease. The heterocycle, which is a fused ring, has a high pharmacological quality. A pteridine is one of the heterocycles that has attracted a lot of interest in terms of biological uses. The pteridine nucleus serves as the quintessential framework in a range of physiologically energetic chemicals and pharmacological molecules. This evaluation is necessary in order to bring to light the remarkable potential that this ring device possesses as a result of the wide variety of pharmacological effects it may perform. This research might unquestionably hasten the graph and synthesis procedures, which would ultimately yield in a wide array of therapeutically feasible medicinal options. Keywords: Pteridine, Anti-tumour, Cancer Cell-lines, Tumourgrowh. INTRODUCTION Chemists in medicinal chemistry strive to create, investigate, and manufacture medications or drugs that will help humanity. The chemistry of heterocyclic molecules is critical in the development of novel medications. A pteridine is an aromatic heterocycle that results from the reaction of pyrimidine with pyrazine. Pteridine derivatives are mostly obtained from insects wings, (Pterones means wings in Greek). 1 Pteridine, basic nucleus are yellow in colour and its derivatives are mostly coloured compounds. Compounds made up of fused pyrimidine and pyrazine rings. Pteridine research has long been recognized as critical to many biological processes, thatincludes amino