World Journal of AIDS, 2016, 6, 37-41
Published Online June 2016 in SciRes. http://www.scirp.org/journal/wja
http://dx.doi.org/10.4236/wja.2016.62005
How to cite this paper: Ezeibe, M.C.O., Aleeyu, D., Ogbonna, I.J. and Kalu, E. (2016) Clinical Trial of Medicinal Synthetic
Aluminum-Magnesium Silicate (Antivirt
®
) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients. World Journal
of AIDS, 6, 37-41. http://dx.doi.org/10.4236/wja.2016.62005
Clinical Trial of Medicinal Synthetic
Aluminum-Magnesium Silicate (Antivirt
®
)
on Viral Loads and CD4-Lymphocytes
Counts of HIV/AIDS Patients
Maduike C. O. Ezeibe
1
, Dahiru Aleeyu
2
, Ijeoma J. Ogbonna
1
, Ekenma Kalu
1
1
College of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike, Nigeria
2
Basic Health Clinic, Abuja, Nigeria
Received 28 January 2016; accepted 19 April 2016; published 22 April 2016
Copyright © 2016 by authors and Scientific Research Publishing Inc.
This work is licensed under the Creative Commons Attribution International License (CC BY).
http://creativecommons.org/licenses/by/4.0/
Abstract
For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt
®
), on viral
loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Their blood
samples were tested for viral loads and for CD4-lymphocytes counts, before the treatment and
every 4 weeks during the medication. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized
Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection
®
(1 tablet/day), for 4 weeks.
Then, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When their viral loads be-
come undetectable, they would be treated for additional 4 weeks. Initially, the Antivirt
®
-regimen
appeared to worsen both HIV infection-load and immune deficiency but later relieved them. Pa-
tients’ mean-viral load increased (P = 0.020), from 1820.30 ± 868.75 to 2855.90 ± 960.98, after 4
weeks before reducing (P = 0.030) to 1565.20 ± 743.17, after 8 weeks. Similarly, their mean-CD4-
lymphocytes count reduced (P = 0.008) from 496.80 ± 194.39 to 263.90 ± 149.26, after 4 weeks
before improving (P = 0.001) to 507.90 ± 133.19, after 8 weeks.
Keywords
Antivirt
®
, Nanoparticles, Destroying Infected Cells, Unmasking “Hidden Infections”,
Mopping-Out HIV
1. Introduction
Molecules of Aluminum-magnesium silicate (AMS) are made of Nanoparticles [1] [2] which have negative