Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/iej.13028 This article is protected by copyright. All rights reserved. DR. ERICK MIRANDA SOUZA (Orcid ID : 0000-0003-2074-0834) PROF. GUSTAVO DE-DEUS (Orcid ID : 0000-0001-7778-047X) DR. MONTSE MERCADÉ (Orcid ID : 0000-0003-1303-3787) Article type : Original Scientific Article Effectiveness of complementary irrigation routines in debriding pulp tissue from root canals instrumented with a single reciprocating file. P Varela 1 , E Souza 2 , G de Deus 3 , F Duran-Sindreu 1 , M Mercadé 4 1 Department of Endodontics, Universitat Internacional de Catalunya, Barcelona, Spain, 2 Department of Dentistry II, Federal University of Maranhão, São Luis, Brazil. 3 Department of Endodontics, Grande Rio University, Duque de Caxias, Brazil 4 Department of Dentistry, Universitat de Barcelona, Barcelona, Spain; Researcher, IDIBELL Institute, Barcelona, Spain. Running Title: effectiveness of complementary irrigation routines Keywords: Endodontic disinfection, passive ultrasonic irrigation, sonic activation, manual dynamic activation