Accepted Manuscript Title: A combination of nanosystems for the delivery of cancer chemoimmunotherapeutic combinations: 1-methyltryptophan nanocrystals and paclitaxel nanoparticles. Authors: P. Calleja, JM Irache, C. Zandueta, C. Mart´ ınez-Oharriz, S. Espuelas PII: S1043-6618(17)30198-6 DOI: http://dx.doi.org/10.1016/j.phrs.2017.09.004 Reference: YPHRS 3679 To appear in: Pharmacological Research Received date: 15-2-2017 Revised date: 5-9-2017 Accepted date: 7-9-2017 Please cite this article as: Calleja P, Irache JM, Zandueta C, Mart´ ınez- Oharriz C, Espuelas S.A combination of nanosystems for the delivery of cancer chemoimmunotherapeutic combinations: 1-methyltryptophan nanocrystals and paclitaxel nanoparticles.Pharmacological Research http://dx.doi.org/10.1016/j.phrs.2017.09.004 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.