Copyright@ Ukoha-kalu Blessing Onyinye | Biomed J Sci & Tech Res | BJSTR. MS.ID.005160. 24496 Research Article ISSN: 2574 -1241 Prevalence of Uncontrolled Blood Pressure and Drug Related Problems in Adult Hypertensive Patients: A Comparative Study Ukoha-kalu Blessing Onyinye*, Adibe Maxwell Ogochukwu and Ukwe Chinwe Victoria Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria, Nigeria *Corresponding author: Ukoha-kalu Blessing Onyinye, Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria, Nigeria DOI: 10.26717/BJSTR.2020.31.005160 ARTICLE INFO ABSTRACT Background: DRPs are one of the major challenges to health care providers as this may affect morbidity, mortality and patients’ quality of life. Objective: This study aimed to compare the prevalence of uncontrolled blood pressure and drug therapy problems in two Nigerian tertiary institutions. Methods: This was a retrospective cross sectional study carried out in the Department of Internal Medicine, University of Nigeria Teaching Hospital (UNTH), Ituku/Ozalla, Enugu state and Federal Medical Centre Lokoja (FMCL), Kogi State, over a period of two months (June1, 2019- July 31, 2019). Ethical clearance for the study was obtained from the Health and Research ethics committee of both hospital. A well designed proforma adopted from similar studies was used to collect patients’ socio-demographic and clinical variables from their folders. Pharmaceutical Care Network Europe (PCNE) Classification tool Version8.02 (PCNE, 2010) was used to document the types and causes of Drug therapy problems. The data cleaning was conducted in Microsoft excel after which information were exported and analysed using the Statistical Package for Social Sciences (SPSS for windows, Version 16.0. SPSS Inc. 2007.Chicago, USA) software. Continuous data were presented as mean ± standard deviation while categorical data were presented as percentages and frequencies. Results: The ratio of male to female patients was 1.03: 1 with a greater number of the patients being above 55 years of age. the ratio of controlled blood pressure to uncontrolled blood pressure was 1:1.02 for UNTH and 1:0.601 for FMCL. FMCL recorded a percentage of patients with uncontrolled blood pressure. Older patients had more DTPs than the younger ones and this was statistically significant. Blood pressure control was associated with age in both study centres as increase in age decreased blood pressure control and this was statistically significant. Conclusion: Blood pressure control in both centres were below average while prevalence of DRPs was high in both centres too. An educational interventional programmes is recommended to enlighten patients on the need adopt lifestyle modifications to control their blood pressure and the dangers of uncontrolled blood pressure. Received: October 22, 2020 Published: November 11, 2020 Citation: Ukoha-kalu Blessing Onyinye, Adibe Maxwell Ogochukwu, Ukwe Chinwe Victoria. Prevalence of Uncontrolled Blood Pressure and Drug Related Problems in Adult Hypertensive Patients: A Comparative Study. Biomed J Sci & Tech Res 31(5)-2020. BJSTR. MS.ID.005160. Keywords: Hypertension; Blood Pressure Control; Drug Related Problems Abbreviations: UNTH: University of Nigeria Teaching Hospital; FMCL: Federal Medical Centre Lokoja; PCNE: Pharmaceutical Care Network Europe; SPSS: Statistical Package for Social Sciences Introduction DRPs are one of the major challenges to health care providers as this may affect morbidity, mortality and patients’ quality of life [1]. DRPs have been found to lead to reduced quality of life, increased hospital stay, increased overall health care cost with an increase in morbidity and mortality [2]. Also, inappropriate use of drugs are harmful and can possibly evoke side effects [3]. Clinical pharmacists in coordination with other health care providers can identify DRPs through medication reconciliation [4]. Although there are several classifications of DRPs, there is no single standardized classification