DMD #44057 1 Effect of albumin on human liver microsomal and recombinant CYP1A2 activities: Impact on in vitro-in vivo extrapolation of drug clearance Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J. Elliot, Kushari Bowalgaha, Kathleen M. Knights and John O. Miners Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand (NW and WT) and Research and Diagnostic Center for Emerging Infectious Disease, Khon Kaen University (WT) Department of Clinical Pharmacology, School of Medicine, Flinders University, Adelaide, Australia (AR, DJE, KB, KMK and JOM) DMD Fast Forward. Published on February 13, 2012 as doi:10.1124/dmd.111.044057 Copyright 2012 by the American Society for Pharmacology and Experimental Therapeutics. This article has not been copyedited and formatted. The final version may differ from this version. DMD Fast Forward. Published on February 13, 2012 as DOI: 10.1124/dmd.111.044057 at ASPET Journals on December 19, 2023 dmd.aspetjournals.org Downloaded from