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Diabetes Research and Endocrinology
2018
Vol.2No.1:1
1
© Under License of Creative Commons Attribution 3.0 License | This article is available from: http://www.imedpub.com/diabetes-research-and-endocrinology
Research Article
Neha Sudhera*,
Ginjinder Kaur,
Deepkiran Bassi,
Gurinder Singh and
Kulvir Singh
Department of Human Genetcs, Punjabi
University, Patala, India-147002
Corresponding author: Neha Sudhera
neha_sudhera@yahoo.com
Department of Human Genetcs, Punjabi
University, Patala, India-147002.
Tel: 09780680392
Citaton: Sudhera N, Kaur G, Bassi D,
Singh G, Singh K (2018) Prevalence of
Metabolic Syndrome in the Type 2 Diabetes
Populaton of North-West Punjab. J Diabetes
Res Endocrinol. Vol. 2 No.1:1
Prevalence of Metabolic Syndrome
in the Type 2 Diabetes Populaton of
North-West Punjab
Abstract
Background: Type 2 diabetes is a complex disorder and metabolic syndrome
in combinaton with diabetes leads to increased risk of microvascular and
macrovascular complicatons due to associated dyslipidemia, hypertension and
obesity. The present study evaluates the prevalence of metabolic syndrome in type
2 diabetes patents and the risk factors associated with the metabolic syndrome.
Methods: Fastng blood samples of 680 diabetes patents (340 males and 340
females) were collected with informed consent. The lipid profle, blood pressure
and anthropometric parameters (weight, height and waist measurements) were
assessed using standardized techniques. The criteria given by IDF (2006) were
used for assessment of metabolic syndrome.
Findings: The prevalence of metabolic syndrome was signifcantly higher in females
(43.5%) as compared to males (34.1%). The prevalence of metabolic syndrome
was more in females in the age group 31-40 years (29.1%) and 41-50 years (29.1%)
whereas in males, the prevalence was more in 41-50 years (44.8%) and 51-60 years
(44.8%) age groups. In females, central obesity (81.7%) and hypertension (64.7%)
followed by hypertriglyceridemia (68.1%) were the driving forces for metabolic
syndrome whereas in males, it were hypertriglyceridemia (68.1%) and central
obesity (67.3%), followed by hypertension (59.4%). Based on BMI, 27.4% males
were overweight; 55% were obese and only 17.6% had normal BMI whereas in the
females, 15.6% were overweight; 75.9% were obese and only 8.5% had normal
BMI ranges. The male diabetes patents with metabolic syndrome had clustering
of central obesity and diabetes with any two other risk factors and in females, it
was central obesity and diabetes with any one risk factor. Only few individuals had
clustering of all the risk factors.
Conclusion: MetS risk factors were high among this populaton. Increased serum
triglyceride for men and central obesity for women were the strongest risk factors.
Metabolic syndrome is a signifcant health problem that needs to be tackled with
proven strategies.
Keywords: Type 2 diabetes; Glucose tolerance; Metabolic syndrome; Triglycerides
Abbreviatons: BMI: Body Mass Index; DBP: Diastolic Blood Pressure; HDL: High
Density Lipoprotein; IDF: Internatonal Diabetes Federaton; MetS: Metabolic
Syndrome; NCEP ATP-III: Natonal Cholesterol Educaton Program Adult Treatment
Panel III; SBP: Systolic Blood Pressure; TG: Triglycerides; WC: Waist Circumference;
WHO: World Health Organizaton
Received: January 18, 2018; Accepted: February 20, 2018; Published: March 01, 2018