Accepted Manuscript The effect of binder concentration and dry mixing time on granules, tablet characteristics and content uniformity of low dose drug in high shear wet granulation Gamal M. Mahours, Diaa Edin Z. Shaaban, Gamal A. Shazly, Sayed H. Auda PII: S1773-2247(16)30576-7 DOI: 10.1016/j.jddst.2017.03.014 Reference: JDDST 321 To appear in: Journal of Drug Delivery Science and Technology Received Date: 22 November 2016 Revised Date: 2 March 2017 Accepted Date: 18 March 2017 Please cite this article as: G.M. Mahours, D.E.Z. Shaaban, G.A. Shazly, S.H. Auda, The effect of binder concentration and dry mixing time on granules, tablet characteristics and content uniformity of low dose drug in high shear wet granulation, Journal of Drug Delivery Science and Technology (2017), doi: 10.1016/j.jddst.2017.03.014. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.