_____________________________________________________________________________________________________ *Corresponding author: E-mail: ottaman15@gmail.com; Curr. J. Appl. Sci. Technol., vol. 42, no. 9, pp. 6-21, 2023 Current Journal of Applied Science and Technology Volume 42, Issue 9, Page 6-21, 2023; Article no.CJAST.97209 ISSN: 2457-1024 (Past name: British Journal of Applied Science & Technology, Past ISSN: 2231-0843, NLM ID: 101664541) Mathematical Model on the Control/Eradication of the Consumption of Cannabis sativa in Afikpo North Local Government Area of Ebonyi State, Nigeria U. S. Isienyi a* , E. C. Arihilam b , F. A. Ujah a , and V. U. Olugbue c a Department of Maths/Statistics, Akanu-Ibiam Federal Polytechnic, Unwana, P.M.B 1007, Afikpo, Ebonyi State, Nigeria. b Department of Civil Engineering Technology, Akanu-Ibiam Federal Polytechnic, Unwana, P.M.B 1007, Afikpo, Ebonyi State, Nigeria. c Department of Science Laboratory Technology, Akanu-Ibiam Federal Polytechnic, Unwana, P.M.B 1007, Afikpo, Ebonyi State, Nigeria. Authors’ contributions This work was carried out by all the authors. Author IUS did the model formulation and designed the study. Author UFA did work simulation. Authors AEC and OVU revised the manuscript. All authors read and approved the final manuscript. Article Information DOI: 10.9734/CJAST/2023/v42i94090 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/97209 Received: 05/01/2023 Accepted: 07/03/2023 Published: 24/04/2023 ABSTRACT The present work studied the dynamics of the interaction of the susceptible and victims of Cannabis sativa smoking/consumption using a mathematical model SEIR (Susceptible, Exposed, Infected, and Recovered/Removed) approach with sensitive control parameters introduced accordingly. We Original Research Article