Dewi Pranatasari, et. al. 250 Jurnal Sain Veteriner, Vol. 39. No. 3. Desember 2021, Hal. 250-255 DOI : 10.22146/jsv.66420 ISSN 0126-0421 (Print), ISSN 2407-3733 (Online) Tersedia online di https://jurnal.ugm.ac.id/jsv Daya Antelmintik Serbuk Kulit Nanas (Ananas Comosus) terhadap Cacing Haemonchus Contortus pada Domba The Anthelmintic Potency Of Pineapple (Ananas Comosus) Peel Powder against Haemonchus Contortus Worm in Sheep Dewi Pranatasari, Rido Florensius Manik, Budi Purwo Widiarso, Wida Wahidah Mubarokah * Politeknik Pembangunan Pertanian Yogyakarta Magelang, Jl. Magelang- Kopeng Km 7 Purwosari, Tegalrejo, Magelang, Jawa Tengah *Corresponding author, email: wida_wahidah02@yahoo.co.id Naskah diterima: 7 Juni 2021, direvisi: 22 Juli 2021, disetujui: 30 November 2021 Abstract The problem facing sheep breeders in breeding sheep was digestive tract parasite of worm (nematodiasis and haemonchosis). Resistance to anthelmintics was the reason for the study of alternative medication of H. contortus infection. It aimed at fnding out the efectiveness of the application of pineapple peel powder as H. contortus anthelmintic in sheep and the dose of the pineapple peel powder as the H. contortus anthelmintic. It used 15 sheep that were assigned to 5 groups. Group I served as positive control with the application of albendazole (Kalbazen) anthelmintic, Group II was treated using the pineapple peel powder at the dose of 150 mg/kg BW. Group III was treated using the pineapple peel powder at the dose of 200 mg/kg BW. Group IV was treated using the pineapple peel powder at the dose of 250 mg/kg BW. And, Group V served as negative control without any treatment. The treatments were conducted for 14 days and were analyzed using comparative descriptive method by comparing initial data (before the treatments) and fnal data (after the treatments). The comparative data showed that there was signifcant change in the observed variables. The results of the study showed that the pineapple peel powder could be used as the anthelmintic of the H. contortus in the sheep and the dose of 250 mg/kg BW most signifcantly decreased the mean number of the eggs of the worm per gram of feces. Keywords: anthelmintic; Haemonchus contortus; pineapple peel powder; sheep Abstrak Permasalahan yang dihadapi peternak dalam melakukan budidaya ternak domba adalah gangguan parasit saluran pencernaan, berupa cacingan (nematodiasis atau haemonchosis). Adanya resistensi terhadap antelmintik menyebabkan pengembangan penelitian mengenai alternatif pengobatan terhadap H. Contortus.Penelitian ini bertujuan untuk mengetahui efektiftas pemberian serbuk kulit nanas sebagai obat cacing Haemonchus contortus pada ternak domba dan mengetahui dosis penggunaan serbuk kulit nanas sebagai obat cacing Haemonchus contortus. Penelitian ini menggunakan 15 ekor domba yang dibagi dalam 5 kelompok. Kelompok I sebagai kontrol positif diberikan obat cacing albendazol (Kalbazen); kelompok II diberi perlakuan serbuk kulit nanas dosis 150 mg/kg BB; kelompok III diberi serbuk kulit nanas 200 mg/kg BB; kelompok IV diberi serbuk kulit nanas 250 mg/kg BB dan kelompok V sebagai kontrol negatif atau tanpa perlakuan. Perlakuan diberikan selama 14 hari dan hasil kemudian dianalisis dengan analisis diskriptif komperatif, yaitu dengan membandingkan hasil awal (sebelum perlakuan) dengan data akhir (setelah perlakuan). Berdasarkan hasil dari perbandingan data tersebut akan diketahui perubahan variabel yang akan