This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/pai.13323 This article is protected by copyright. All rights reserved DR PARISA AMIRIFAR (Orcid ID : 0000-0002-7782-824X) DR GHOLAMREZA AZIZI (Orcid ID : 0000-0001-5658-2511) PROFESSOR ASGHAR AGHAMOHAMMADI (Orcid ID : 0000-0002-4870-0394) DR REZA YAZDANI (Orcid ID : 0000-0002-5578-6595) Article type : Original Clinical, Immunological and Genetic findings in Patients with UNC13D Deficiency (FHL3): a Systematic Review Parisa Amirifar 1,2# , Mohammad Reza Ranjouri 2# , Hassan Abolhassani 3,4 , Tannaz Moeini Shad 2 , Amir Almasi-Hashiani 5 , Gholamreza Azizi 2,6 , Soraya Moamer 7 , Asghar Aghamohammadi 2 , Reza Yazdani 2* 1 Department of Medical Genetics, School of Medicine, Tehran University of medical sciences, Tehran, Iran 2 Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran, and the University of Medical Science, Tehran, Iran 3 Research Center for Primary Immunodeficiencies, Iran University of medical sciences, Tehran, Iran 4 Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institute at Karolinska University Hospital Huddinge, Stockholm, Sweden 5 Department of Epidemiology, Arak University of Medical Sciences, Arak, Iran 6 Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran Accepted Article