© 2019 Scholars Journal of Applied Medical Sciences | Published by SAS Publishers, India 1702 Scholars Journal of Applied Medical Sciences Abbreviated Key Title: Sch J App Med Sci ISSN 2347-954X (Print) | ISSN 2320-6691 (Online) Journal homepage: https://saspublisher.com/sjams/ Cytopathological Study of Peritoneal Washings and Ascitic Fluid in Gynaecological Malignancies with Histopathological Correlation Dr. Puja A Pingle 1* , Dr. Sujata R Kanetkar 2 , Dr. Sangeeta J Pawar 3 , Dr. Robina M Nazeer 1 , Dr. Sonal O Gupta 1 , Dr.Chetan Khurana 1 1 Post graduate student, 2 Professor & Head of Department, 3 Assistant Professor, Department of Pathology, Krishna Institute of Medical Sciences, Deemed to be University, Karad, Maharashtra, India *Corresponding author: Puja Annasaheb Pingle | Received: 04.05.2019 | Accepted: 04.05.2019 | Published: 30.05.2019 DOI: 10.21276/sjams.2019.7.5.6 Abstract Original Research Article Background: Gynaecological malignancies are one of the leading causes of morbidity and mortality in women. Early detection and prompt management is the key to improve survival rate among affected so we planned to do study of cytopathological examination of peritoneal washings and ascitic fluid in gynecological malignancies as it is a simple & inexpensive method and correlate the findings with histopathological diagnosis and clinical information to arrive at staging and local spread of disease. Aim & objectives: To study cytopathology of peritoneal washings and ascitic fluid in gynaecological malignancies with histopathological correlation along with clinical details in gynaecological malignancies and to correlate cytopathological findings with staging of gynaecological malignancies. Material and methods: This study was carried out in Department of Pathology of a tertiary care hospital. This was a cross sectional study of cytopathological examination of peritoneal washings and ascitic fluid in gynaecological malignancies with histopathological correlation. Period of study was 2 years from June 2016 to May 2018, which includes 40 cases. Results: In present study total 40 samples from cases of Gynaecologic malignancies were received from our hospital which includes 14 samples of ascitic fluid (35%) and 26 samples of peritoneal wash (65%) for cytopathological studies. Out of 40 gynaecological malignancies, ovarian malignancies predominates (87.5%) Conclusion: Cytopathological examination of ascitic fluid and peritoneal washing greatly aids in supporting the diagnosis, in predicting the prognosis and chance of recurrence of the tumor that in turn helps in proper management and treatment of the patients. Keywords: Peritoneal washings, Ascitic fluid, Gynaecologic malignancies. Copyright @ 2019: This is an open-access article distributed under the terms of the Creative Commons Attribution license which permits unrestricted use, distribution, and reproduction in any medium for non-commercial use (NonCommercial, or CC-BY-NC) provided the original author and source are credited. INTRODUCTION Gynaecological malignancies are one of the leading causes of morbidity and mortality in women [1]. Early detection and prompt management is the key to improve survival rate among affected. Methods of detection of microscopic disease are therefore of significant interest and may reduce mortality rate by enabling an earlier diagnosis of gynaecological malignancies [2]. Ascitic fluid cytology and peritoneal washings is important tool that help in diagnosis and prognosis of gynaecological malignancies. Peritoneal washings were initially described in 1956 for the evaluation of gynecologic malignancies. The purpose of this procedure was to diagnose “early” spread of cancer [3]. The presence of malignant cells in peritoneal washings reflects intraperitoneal spread of the neoplastic process beyond the primary organ site. When this occurs, it often correlates with a poor prognosis in variety of tumors. We planned to do study of cytopathological examination of peritoneal washings and ascitic fluid in gynecological malignancies as it is a simple & inexpensive method and correlate the findings with histopathological diagnosis and clinical information to arrive at staging and local spread of disease. MATERIAL AND METHODS This study was carried out in Department of Pathology of a tertiary care hospital. This was a cross sectional study of cytopathological examination of peritoneal washings and ascitic fluid in gynaecological malignancies with histopathological correlation. Period of study was 2 years from June 2016 to May 2018, which includes 40 cases. Urology