BRIEF REPORT Prevalence and Risk Factors of Sleep Disturbance in a Large HIV-Infected Adult Population C. Allavena 1,2 • T. Guimard 2,3 • E. Billaud 1,2 • S. De la Tullaye 4 • V. Reliquet 1,2 • S. Pineau 2 • H. Hu ¨e 1,2 • C. Supiot 1,2 • J.-M. Chennebault 2,5 • C. Michau 2,6 • H. Hitoto 2,7 • R. Vatan 2,8 • F. Raffi 1,2 • The COREVIH-Pays de la Loire Troubles du Sommeil Study Group Ó Springer Science+Business Media New York 2015 Abstract This cross-sectional study evaluates the preva- lence and factors associated with sleep disturbances in French adult HIV-infected outpatients. Patients fullfilled a self-administered questionnaire on their health behavior, sleep attitudes (Pittsburgh sleep quality index, PSQI), quality of life and depression; 1354 patients were enrolled. Median sleeping time was 7 h. Poor sleep quality was observed in 47 % of the patients, and moderate to serious depressive symptoms in 19.7 %. Factors significantly associated with sleep disturbances were depression, male gender, active employment, living single, tobacco-smok- ing, duration of HIV infection, nevirapine or efavirenz- including regimen. Prevalence of poor sleepers is high in this HIV adult outpatient population. Associated factors seem poorly specific to HIV infection and more related to social and psychological status. Taking care of these disturbances may prove to be an effective health manage- ment strategy. Resumen Este estudio transversal evalu ´ a la prevalencia y los factores asociados con los trastornos del suen ˜o en adultos franceses pacientes en ambulatorio infectados por el VIH. Los pacientes completan un auto-cuestionario sobre su comportamiento de salud, las actitudes del suen ˜o (Pittsburgh Sleep Quality Index, PSQI), la calidad de vida y la depresio ´n; 1354 pacientes fueron incluidos. La med- iana del tiempo de suen ˜ o fue de 7 horas. La malacalidad del suen ˜o se observo ´ en el 47 % de los pacientes, y moderados a graves sı ´ntomas depresivos en 19,7 % de los pacientes. Los factores asociados significativamente con las altera- ciones del suen ˜o son: la depresio ´n, el sexo masculino, trabajador activo, viviendo solo, fumador, la duracio ´n de la infeccio ´n VIH, tratamiento nevirapina o efavirenz. La prevalencia de los trastornos del suen ˜o es alta en esta poblacio ´n de pacientes adultos VIH en ambulatorio. Los factores asociados parecen poco relacionados a la infeccio ´n VIH y ma ´s relacionados con el estatus social y psicolo ´gico. El cuidado de estos trastornos puede ser una estrategia eficaz en la gestio ´n de la salud. Keywords Sleep disturbance Á Insomnia Á Depression Á HIV infection Introduction Sleep disturbances are common in HIV populations, esti- mated as occurring in as many as 70 % in some studies, most of them performed early in the HIV epidemic [1]. In the HIV population, anxiety regarding a potential fatal illness, financial concerns, stigmatization, depression, and The members of COREVIH-Pays de la Loire Troubles du Sommeil Study Group are listed in Appendix. & C. Allavena Clotilde.allavena@chu-nantes.fr 1 Infectious Diseases Department, CHU Ho ˆtel-Dieu, University of Nantes, Nantes, France 2 COREVIH Pays de la Loire, Nantes, France 3 Infectious Diseases department, CHD Vende ´e, La Roche sur Yon, France 4 CHU, Explorations fonctionnelles, University of Nantes, Nantes, France 5 Infectious Diseases Department, CHU, Angers, France 6 Internal Medicine Department, CH, St Nazaire, France 7 Infectious Diseases Department, CH, Le Mans, France 8 Internal Medicine Department, CH, Laval, France 123 AIDS Behav DOI 10.1007/s10461-015-1160-5