Jemds.com Original Research Article J. Evolution Med. Dent. Sci./eISSN- 2278-4802, pISSN- 2278-4748/ Vol. 6/ Issue 27/ Apr. 03, 2017 Page 2264 ROLE OF MULTIDETECTOR CT IN IMAGING OF LYMPHOMA Shivraj Marotirao Ingole 1 , Reshma Prakash Chavan 2 , Tushar Madhavrao Kalekar 3 , Prashant G. Pote 4 , Shilpa V. Domkundwar 5 , Sharad M. Malvadhkar 6 , Sharad B. Ghatge 7 , Varsha Pratik Rathi 8 1 Associate Professor, Department of Radiology, GMC and Sir J. J. Group of Hospitals, Mumbai. 2 Associate Professor, Department of Otorhinolaryngology, Dr. V. M. Medical College, Solapur. 3 Associate Professor, Department of Radiology, Dr. D. Y. Patil Medical College, Pune. 4 Senior Resident, Department of Radiology, GMC and Sir J. J. Group of Hospitals, Mumbai. 5 Professor and HOD, Department of Radiology, GMC and Sir J. J. Group of Hospitals, Mumbai. 6 Associate Professor, Department of Radiology, GMC and Sir J. J. Group of Hospitals, Mumbai. 7 Associate Professor, Department of Radiology, GMC and Sir J. J. Group of Hospitals, Mumbai. 8 Professor, Department of Radiology, GMC and Sir J. J. Group of Hospitals, Mumbai. ABSTRACT BACKGROUND Lymphomas are one of the common neoplasms of the patients in the young age group. Accurate staging of the patients is very important in planning appropriate therapy. MATERIALS AND METHODS The study was a retrospective survey from 2004 to 2005. CT scan abdomen was performed in 80 patients of histological proved lymphoma. CT guided fine needle aspiration cytology were also performed where indicated by the referring physician. RESULTS In this retrospective male preponderance study of 80 patients with proven lymphoma, positive findings were seen in 57 (71.2%) patients with 46% of HD and 84% of NHL patients showed intra-abdominal involvement. CT accurately detected nodal and extra nodal sites of involvement. Lymph node involvement was the most common manifestation of lymphoma and it was seen in 66% of all the patients. CT showed the exact sites, the pattern of involvement, the morphological features and associated complications. In both HD and NHL. Extranodal involvement was detected in patients. The involvement of liver was seen in 28%, spleen in 26.3%, GIT in 14% and renal involvement was seen in 7% of the patients with positive findings. Other sites of involvement include pancreas, psoas muscle and vertebrae. CONCLUSION The accuracy of CT in the staging of patients with lymphoma is widely recognised, and it is now the first investigation of choice in the initial staging and followup of these patients. Most centres now rely on biopsy of one group of nodes for diagnosis and stage the patient based on imaging with CT and haematological assessment including bone marrow biopsy. KEYWORDS Lymphoma, Lymphoma Staging, Lymph Node, Computed Tomography. HOW TO CITE THIS ARTICLE: Ingole SM, Chavan RP, Kalekar TM, et al. Role of multidetector CT in imaging of lymphoma. J. Evolution Med. Dent. Sci. 2017;6(27):2264-2269, DOI: 10.14260/Jemds/2017/487 BACKGROUND Lymphomas are malignant tumours of lymphoreticular origin, i.e. from lymphocytes and histiocytes and their precursor cells. Clinically and pathologically, lymphomas are quite heterogeneous. However, two distinct clinical pathologic groups are routinely distinguished; Hodgkin’s Disease (HD) and Non-Hodgkin’s Lymphoma (NHL). (1) They are one of the common neoplasms of the patients in the young age group. Financial or Other, Competing Interest: None. Submission 10-02-2017, Peer Review 19-03-2017, Acceptance 23-03-2017, Published 03-04-2017. Corresponding Author: Dr. Shivraj Marotirao Ingole, Flat No 4, Swastik Building, Sir J. J. Hospital Campus, Byculla, Mumbai-08. E-mail: drshivraj@gmail.com DOI: 10.14260/jemds/2017/487 Accurate staging of the patients is very important in planning appropriate therapy, as advent of newer chemotherapeutic regimens and radiotherapy planning has improved the outcome with aim of achieving total cure rather than palliative cure. A series of examinations were performed for this purpose. In the past, lymphography was performed as primary investigation to assess the retroperitoneal lymphadenopathy. (2) It is highly accurate in the detection of macroscopic nodal abnormalities. The limitations are few, although the nodes above cisterna chyli in the root of mesentery and in the hepatic or splenic hili are not demonstrated. Exploratory laparotomy was undertaken to further stage patients when bone marrow biopsy did not reveal any tumour. (3) Ultrasound is a useful survey technique for bulky retroperitoneal lymphadenopathy and can also detect isolated enlarged nodes or groups of nodes in the other areas. But main disadvantages are the operator dependency and suboptimal evaluation due to excessive bowel gases and obesity. (4) Computed Tomography (CT) is a more accurate method in this regard and in addition