~ 9 ~ American Journal of Essential Oils and Natural Products 2017; 5(4): 09-13 ISSN: 2321-9114 AJEONP 2017; 5(4): 09-13 © 2017 AkiNik Publications Received: 14-08-2017 Accepted: 15-08-2017 DT Asilbekova Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan KhM Bobakulov Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan SA Sasmakov Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan JM Abdurakhmanov Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan ShS Azimova Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan ND Abdullaev Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan Sh Sagdullaev Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan Correspondence: KhM Bobakulov Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent, Uzbekistan Composition and antimicrobial activity of essential oils from Daucus carota L. subsp. carota, growing in Uzbekistan DT Asilbekova, KhM Bobakulov, SA Sasmakov, JM Abdurakhmanov, ShS Azimova, ND Abdullaev and Sh Sagdullaev Abstract The study describes the component composition and antimicrobial activity of essential oils from different part of wild carrot (Daucus carota L. subsp. carota, family Apiaceae), growing in Uzbekistan. The essential oils from fruits and aerial parts enriched with oxygenated sesquiterpenes (70.0-88.0%), with high content of carotol (68.3-78.3%). The extracted from fruits essential oils possess expressed activity against opportunistic pathogenic fungus of Candida albicans. Keywords: Daucus carota L. subsp. carota, essential oils, hydro-distillation, GC/MS, antimicrobial activity 1. Introduction The wild carrot Daucus carota L. subsp. carota, belonging to the family (Apiaceae), originally cultivated as a medicinal plant, and then cultured (cultivated form - Daucus carota var sativus Holfm.). In the wild form it is widespread in Central Asia, Western Europe, in the Caucasus, and is very diverse on variety and chemical composition [1, 2] . Different parts of carrot contain essential oils (EO), flavonoids, coumarins, anthocyanins, lipids, falcarindiol and other biologically active compounds [2-13] . In previous scientific studies noted significant differences in EO chemical composition of wild carrots from different regions [5-10, 13] . Component composition of seeds EO of wild carrots depends on the geographical origin of the taxon [7] . Differences in the composition of EO of plants may be due to many factors such as differences in the environmental conditions of the region, season of the collection, the development stage and used extract part of the plant and the method of extraction. In folk medicine, the fruits are used as anthelmintic and diuretic, at nephrolithiasis and flatulence. Whole or parts of wild carrot possess antibacterial, diuretic, choleretic and salt- soluble effect [2] . Depending on the chemical composition of the EO exhibits antioxidant [10] , cytotoxic [9] , antibacterial and antifungal activities [5, 8] . The most significant activity was observed in the essential oils of ripe and unripe fruits of wild carrots, containing as major components α- pinene, sabinene and α-muurolene [5] . It should be noted that was investigated the composition and the biological activity of EOs from seeds of cultivated species of Daucus carota ssp. sativa which commercially available in Uzbekistan. The essential oil from this taxon, containing as main components β-bisabolene (80.49%), β-asarone (8.82%) and β-bergamotene (5.51%) exhibited antimicrobial activity against Staphylococcus aureus and Candida albicans [14] . To the best of our knowledge the EO composition and antimicrobial activities of wild carrot from our region has not been reported. The aim of the present study was to study of the chemical composition and antimicrobial activity of EO of wild carrot (Daucus carota L. subsp. carota), growing in Uzbekistan. The objects of the research were EOs isolated from the ripe fruit, leaves, flowers and petals. 2. Materials and Methods 2.1 Plant material The aerial parts of wild carrot were collected in flowering period (May, 2015) and in the fruiting period (June, 2015) in the Tashkent region of Uzbekistan. The objects were dried for a