Вопросы реконструктивной и пластической хирургии. 2022. Т. 25, № 1. С. 77–82. Issues of Reconstructive and Plastic Surgery. 2022;25(1):77–82. © Sinelnikov M.Ye., Reshetov I.V., Chernosvitova M. et al., 2022 HISTORY OF MEDICINE https://doi.org/10.52581/1814-1471/80/09 УДК 616-089.819:620.3](091)(520) THE HONOURABLE PROFESSOR ISAO KOSHIMA: HISTORICAL CONTRIBUTION FROM MICROSURGERY TO NANOMICROSURGERY M.Ye. Sinelnikov 1 , I.V. Reshetov 1 , Maria Chernosvitova 1 , Arina Khlytina 1 , Maria Kartashova 1 , Yelena Akelina 2 1 I.I. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation 2 Columbia University, New York, USA Abstract In honour of Professor Isao Koshima’s 70th birthday, a short manuscript regarding his main contributions to microsurgery, as well as impact on the surgical specialty in Russian Federation is discussed. The numerous achieve- ments of Professor Koshima are built upon years of experience. Currently, Isao Koshima is the Chief of the Interna- tional Center for Lymphedema, at Hiroshima University Hospital (Japan). He is known be all as an enthusiastic and extremely talented microsurgeon and a world-known scientist. In 1989, I. Koshima first introduced the epigastric artery perforator flap, and the discovery of the DIEP flap is widely accredited to him. He introduced this flap at the 1st International Course on Perforator Flaps held in Ghent in 1997. Professor Koshima’s numerous contributions to the field of microsurgery are truly invaluable. His life and career are respected by all and his guidance is requested daily around the World. I. Koshima’s contribution to lymphatic supermicrosurgery is especially prominent, as this field is completely built upon his pronounced expertise. To this day, Isao Koshima offers lectures, training programs and is an active participant of many congresses worldwide, making him one of the most sought teachers in the his- tory of microsurgery. Keywords: Isao Koshima, short biography, history of microsurgery, history of medicine. Conflict of interest: the authors declare the absence of obvious and potential conflicts of interest related to the publication of this paper. Financial disclosure: no author has a financial or property interest in any material or method metioned. For citation: Sinelnikov M.Ye., Reshetov I.V., Chernosvitova M.D., Khlytina A.A., Kartashova M.K., Akelina Ye. The honourable Isao Koshima: historical contribution from microsurgery to nanomicrosurgery. Issues of Reconstructive and Plastic Surgery. 2022;25(1):77–82. doi 10.52581/1814-1471/80/09 ИСТОРИЯ МЕДИЦИНЫ ИСТОРИЧЕСКИЙ ВКЛАД ИСАО КОШИМЫ В РАЗВИТИЕ МИКРОХИРУРГИИ: ОТ МИКРОХИРУРГИИ ДО НАНОХИРУРГИИ M.Е. Синельников 1 , И.В. Решетов 1 , M.Д. Черновитова 1 , A.А. Хлытина 1 , M.К. Карташова 1 , Е. Акелина 2 1 Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский университет), Москва, Российская Федерация 2 Колумбийский университет, Нью-Йорк, США