Fax +41 61 306 12 34 E-Mail karger@karger.ch www.karger.com Original Article Gynecol Obstet Invest 2006;62:41–44 DOI: 10.1159/000091842 Effect of Membrane Sweeping at Term Pregnancy on Duration of Pregnancy and Labor Induction: A Randomized Trial Maryam Kashanian a Abdolrasool Akbarian a Hamid Baradaran b Mitra Meshki Samiee a Departments of a Obstetrics and Gynecology and b Epidemiology, Iran University of Medical Sciences, Tehran, Iran sweeping group and 4 in the control group). There were no statistically significant differences between these in- dividuals (p = 0.68). Significant vaginal bleeding was not observed in the two groups. Meconium-stained amni- otic fluid was seen in 13 women: 8 in the sweeping group and 5 in the control group. There were no statistically significant differences among the women who had me- conium-stained fluid in case and control groups (p = 0.39).There were no differences between women who had puerperal fever (3 in the sweeping group and 2 in the control group; p = 0.68).12 of the 101 women (6 in each group) had cesarean section performed, but there was no difference betweeen the two groups. Conclu- sion: Sweeping of membranes at 39 weeks of gestation has no significant clinical effect on the duration of preg- nancy. Copyright © 2006 S. Karger AG, Basel Introduction Induction is an artificial initiation of labor before its spontaneous onset for the purpose of delivery of the feto- placental unit. Labor induction is common in obstetric practice, and its rate varies from 9.5 to 33.7% of all preg- nancies annually. If induction is indicated and the status of the cervix is unfavorable, methods for cervical ripening Key Words Membrane sweeping Labor induction Postterm pregnancy Abstract Aim: To evaluate the efficacy of sweeping of fetal mem- branes for induction of labor in uncomplicated term pregnancies. Methods: A randomized controlled trial was performed in 122 pregnant women beyond 39 weeks of gestation with no complications. The women were as- signed to have their membranes swept or not (controls) for labor induction. The main outcome measures includ- ed duration of pregnancy and possible complications of sweeping of membranes, including rupture of mem- branes, postpartum infections, and vaginal bleeding. Re- sults: Twenty-one patients did not give birth in our hos- pital and were, therefore, excluded from the study; 101 women completed the study (51 patients in the control group and 50 women in the study group). There were no statistically significant differences in maternal age, par- ity, birth weight, and Bishop score in the two groups. The mean interval between sweeping (stripping) and vaginal examination until delivery was 7.7 8 (SD) 6.9 and 7.1 8 5.6 days in the sweeping and in the control group, re- spectively (p = 0.61). Of the 101 pregnant women, only 6 patients had premature rupture of membranes (2 in the Received: September 27, 2005 Accepted after revision: January 17, 2006 Published online: March 3, 2006 Maryam Kashanian, MD Departments of Obstetrics and Gynecology, Iran University of Medical Sciences Khajeh Nasir Toosi Ave, Mostaghimi Alley 83 16117 Tehran (Iran) Tel. +98 21 7752 3487, Fax +98 21 7760 7016, E-Mail maryamkashanian@yahoo.com © 2006 S. Karger AG, Basel 0378–7346/06/0621–0041$23.50/0 Accessible online at: www.karger.com/goi