Journal of Molecular Liquids 391 (2023) 123379 Available online 19 October 2023 0167-7322/© 2023 Elsevier B.V. All rights reserved. Synthesis of Adenosine 5-monophosphate monohydrate functionalized mesoporous Ag/CuO/MCM-41 nanostructures for enormous mineralization of insistent organic contaminants and photoinhibition of bacteria Muhammad Sajid a, 1 , Irum Batool a, 1 , Afaq Ullah Khan b , Kamran Tahir a, * , Eman A. Alabbad c , Khulood Fahad Alabbosh d , Hamza S. Al-Shehri e , Hassan M.A. Hassan f , Sameerah I. Al-Saeedi g , Magdi E.A. Zaki h a Institute of Chemical Sciences, Gomal University, D.I. Khan, KP, Pakistan b School of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China c Department of Chemistry, College of Science, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia d Department of Biology, Collage of Science, University of Hail, Hail, Saudi Arabia e Chemistry Division, King Khalid Military Academy, SANG, 1149 Riyadh, Saudi Arabia f Department of Chemistry, College of Science, Jouf University, Sakaka 2014, Saudi Arabia g Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia h Department of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University, Riyadh 11623, Saudi Arabia A R T I C L E INFO Keywords: A-5-MM-Ag/CuO/MCM-41 Hydrothermal method Antibacterial activity Photocatalytic activity Hemolytic activity ABSTRACT An important potential threat for both individuals, as well as the environment, is organic pollution and microbes in water from waste. Numerous industries, such as paper, food processing, cosmetics, plastics, textile, and others, need a lot of colors. Dyes discharged into water bodies have caused several problems for human beings because dyes are not biodegradable. The apparent and unattractive extremely small dye concentration (1 mg/L) also signifcantly infuences a water body. In a manner analogous to this, healthcare-related infections in hospitals have a signifcant cost impact on healthcare systems. Drug-resistant or multi-drug-resistant microorganisms are the main causes of nosocomial infections. The creation of novel antibacterial materials has proven to be one of the largest challenges in the development of a new technique for preventing the spread of ailments associated with healthcare. To get around these obstacles, it is therefore desirable to come up with new techniques and materials. A unique hydrothermally produced mesoporous CuO/MCM-41 nanostructure was created in this context. Additionally, Ag was deposited to create the CuO/MCM-41 nanostructure, and Adenosine 5-monophos- phate monohydrate (A-5-MM) was used to functionalize it. Additionally, incredible photocatalytic activity was achieved under visible light irradiation by rapidly degrading eriochrome black (EB) and bromothymol blue (BTB) dyes. More than 80% of the said dyes were degraded in 60 min. The said result was much lower in dark con- dition. Furthermore, it was discovered that the A-5-MM-Ag/CuO/MCM-41 nanomaterials exhibited notable antibacterial activity in light against Escherichia coli (E. coli), and Bacillus subtilis (B. subtilis), with respective zones of inhibition of 17 ± 0.2 mm, and 21 ± 0.3 mm. 1. Introduction Different unintentional or intentional actions by chemicals of cosmetic or domestic products and agricultural or industrial origin cause water pollution. Water contamination has become an increasingly serious problem. Due to the expansion of the textiles and cosmetics industries, water released from textile manufacturers has long been regarded as a signifcant source of wastewater. Dye pollution is one of the most severe contaminants observed in wastewater and industrial waste. Numerous investigations have demonstrated that dyes with lower concentrations can result in serious illnesses with mortality risk [1–3]. A number of research investigations have concentrated on the * Corresponding author. E-mail address: kamrantahir@gu.edu.pk (K. Tahir). 1 Equal contribution to this paper. Contents lists available at ScienceDirect Journal of Molecular Liquids journal homepage: www.elsevier.com/locate/molliq https://doi.org/10.1016/j.molliq.2023.123379 Received 9 July 2023; Received in revised form 22 September 2023; Accepted 17 October 2023