International Journal of Pharmaceutical Chemistry and Analysis 2023;10(3):140–143 Content available at: https://www.ipinnovative.com/open-access-journals International Journal of Pharmaceutical Chemistry and Analysis Journal homepage: https://www.ijpca.org/ Review Article An overview on topicl gels and camphor and eucalyptus Vishal Raj 1 , Rajni Yadav 1, *, Sandip Prasad Tiwari 1 1 Dept. of Pharmacy, Kalinga University, Faculty of Pharmacy, Chhattisgarh, India ARTICLE INFO Article history: Received 05-06-2023 Accepted 14-07-2023 Available online 15-09-2023 Keywords: Topical gels Pharmaceuticals Eucalyptus ABSTRACT Across all over the world, the science of pharmacy and pharmaceuticals lead to an evolution in a very large aspect. The pharmaceutical industries of many countries with good economical background produces and develops really good medicinal products originating from both natural and artificial sources and one of the product which is highly used by the pharmaceuticals as well as by the cosmetic industries is topical gels. These products along with some other preparations have up lifted the pharmaceutical industries to a new level in the last 2-3 decades. As we know that these gels are applied on the upper most layer of skin so that it can get absorb to the down most layer to reach the systemic circulation by penetrating and crossing the by lipid layer. These gels come with various functionalities like to alter the appearance, for healing factor as well as for making the skin hydrated and filled with collagen again many pharmaceutical industries nowadays create these gels mostly with natural substances so that they can get more positive and beneficial effects and the least amount of adverse effects and almost no toxicological effects. This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. For reprints contact: reprint@ipinnovative.com 1. Introduction One of the medicinal preparations that is used the most frequently worldwide is topical gel. Because topical gels have a higher demand across all age groups and in both sexes, as well as multiple functionalities like pain relief, rehydrating action, anti-wrinkle action, and healing factors, many different pharmaceutical industries, including medicinal and cosmetic factories, produce and develop these gel as their primary preparations. Both types of bases—oil in water and water in oil—are available for these gels. Numerous variables are assessed as these gels are being made, and the preformulation consideration process is also being watched before the gels are manufactured. The gels constitutes the specific API (active pharmaceutical ingredient) along with different excipients and additives * Corresponding author. E-mail address: rajniyadav@kalingauniversity.ac.in (R. Yadav). like preservative, fragrance, glidant and some other binders. During the manufacturing of gels, they undergo various types of chemical and physical changes which are some times irreversible. During the evaluation, some physical and chemical parameters like pH, viscosity, surface tension, absorption rate etc are the primary concern which need to be looked out carefully because they are the primary aspect and comes before the evalution of biological parameter. 1 To create topical gels, they are some specific guideline, rules and regulation that are meant to followed by every industries nd these guidelines are issued by various governing authorities. The need to issue these gudielines is because it contains some specific information regarding the safety of human health, efficacy and potency of the drug which is used, and also some information about its overdose and toxilogical effects. The biggest advantage of using topical gels is that it is user friendly and can be used by any person at any time and at any place because it doesn’t https://doi.org/10.18231/j.ijpca.2023.025 2394-2789/© 2023 Innovative Publication, All rights reserved. 140