https://doi.org/10.34011/jks.v4i1.1505 390 POLA KEPEKAAN ISOLAT BAKTERI KULTUR PUS PADA INFEKSI KULIT DAN JARINGAN LUNAK TERHADAP BERBAGAI ANTIBIOTIKA Sensitivity Patterns Of Pus Culture Bacterial Isolates In Skin And Soft Tissue Infections To Various Antibiotics Iis Kurniati 1* , Risma Nur Inayah 2 Asep Dermawan 3 Yeni Wahyuni 4 1* Program Studi Sarjana Terapan Jurusan Teknologi Laboratorium Medis, Politeknik Kesehatan Bandung Email: rismaquinn@gmail.com ABSTRACT Skin and soft tissue infections are common infections in Indonesia because the air conditions in Indonesia are humid and dusty, so bacteria can easily thrive. This condition is supported by poor hygiene conditions that facilitate the breeding of infectious diseases. One of the efforts to help the government reduce antibiotic resistance is to provide antibiotics based on the results of bacterial patterns and bacterial sensitivity tests to antibiotics. This study aims to identify the pattern of sensitivity of bacterial isolates of pus culture in skin and soft tissue infections to various antibiotics. This research uses descriptive method while the research design is observational analytic. From the results of the research, the most bacteria found were Staphylococcus aureus (29.7%), Streptococcus pyogenes (12.2%), Escherichia coli (10.8%), Klebsiella pneumoniae ssp pneumoniae (9.5%), Enterococcus faecalis (8.1%), Citrobacter freundii (5.4% ), Streptococcus agalactiae (5.4%), Klebsiella oxytoca (4.1%), Pseudomonas aeruginosa (4.1%), Morganella morganii (2.7%), Proteus mirabilis (2.7%), Acinetobacter sp (1.4%), Proteus ssp (1.4%) , Staphylococcus epidermidis (1.4%), Streptococcus dysgalactiae (1.4%). Most of the Gram negatives were resistant above 50% to ampicillin and sensitive 100% to amikacin, while the majority of Gram positives were resistant above 50% to oxacillin, and tetracyclines, 100% sensitive to ampicillin, linezolid, tigecycline, ceftriaxone, thrimethoprim supfamethoxazole. Key words: Bacterial sensitivity pattern, pus, antibiotics