ECONOMIC, SOCIAL, AND LEGAL CONSEQUENCES OF DRUG ABUSE AND ILLICIT TRAFFICKING INCLUDE EMPLOYMENT, LABOUR, CORRUPTION, AND CRIME - A GLOBAL MACRO ECONOMIC ASSESSMENT Dr. G. YOGANANDHAM, Professor& Head, Department of Economics, Director- Centre for Knowledge, Thiruvalluvar University (A State University) Serkkadu, Vellore District, Tamil Nadu, India- 632 115. A. ABDUL KAREEM, Ph.D., Research Scholar, Department of Economics, Thiruvalluvar University (A State University) Serkkadu, Vellore District, Tamil Nadu, India- 632 115. E.MOHAMMED IMRAN KHAN, Ph.D., Research Scholar, Department of Economics, Thiruvalluvar University (A State University) Serkkadu, Vellore District, Tamil Nadu, India- 632 115. Abstract Drug abuse and illicit trafficking are widespread problems that have detrimental effects on society, the economy, and public health. Overdoses, mental health issues, and addiction are prevalent. Community outreach and education are two prevention techniques. To combat illicit trafficking, a multifaceted strategy involving international collaboration, law enforcement, and prevention is needed. This includes addressing economic and social repercussions like decreased production, higher medical expenses, job challenges, corruption, violent crime, property crime, organized crime, and mental health issues. All forms of drugs, including manmade compounds, naturally occurring botanicals, and psychoactive medications, are banned. In 1995, the Commission on Narcotic Drugs carried out studies on drug production, distribution, and use in black markets. The Commission was advised by the General Assembly to address the negative social and economic effects of drug abuse and illicit trafficking. Different estimates constrain our current understanding. Drug misuse and illegal trafficking have a detrimental effect on the economy, society, and culture. They also pose a threat to public health, raise healthcare costs, and lower productivity. Implementing a comprehensive plan for drug abuse and trafficking, including treatment, prevention, education, law enforcement, and legislative changes, is crucial due to increased urbanization and cultural shifts. Notwithstanding the foregoing, the main objectives of this research article are to carry out a global macroeconomic theoretical analysis of the economic, social, and legal ramifications of drug abuse and illicit trafficking, including employment, labour, corruption, and crime, using secondary sources of information and relevant statistical data. According to this point of view, the situation as it stands now is important and relevant to both the economy and society. Keywords: Drug Abuse,Illicit Trafficking,Detrimental Effects, Public Health,Healthcare Costs, Law Enforcement, Psychoactive Medications, Social and Economic Effects. ISSN NO : 1869-9391 PAGE NO: 156 GIS SCIENCE JOURNAL VOLUME 11, ISSUE 1, 2024