International Journal for Multidisciplinary Research (IJFMR) E-ISSN: 2582-2160 Website: www.ijfmr.com Email: editor@ijfmr.com IJFMR23022333 Volume 5, Issue 2, March-April 2023 1 A Modern Era Prospective of Novel Drug Delivery System Prerana Sahu 1, 3 , Prachi Bhimte 2 , Harish Sharma 2 , Gyanesh kumar Sahu 2 * 1 Rungta Institute of Pharmaceutical Sciences 2 Rungta Institute of Pharmaceutical Sciences and Research 3 Rungta College of Pharmaceutical Sciences and Research Corresponding author: Dr. Gyanesh Kumar Sahu Professor & Dean Rungta Institute of Pharmaceutical Sciences and Research Email ID- gyanesh.sahu23@gmail.com Contact Number- +91-9907749963 ABSTRACT Novel Drug delivery system is an approach to formulate technologies and system for transporting a pharmaceutical compound into the body to achieve its desired therapeutic effect. In the recent times conventional dosage form were used frequently. But novel drug delivery is an advance technique that has replaced conventional dosage form increasingly. It has proved itself in showing better patient compliance, safety and efficacy. The main aim for developing such delivery system is to minimize drug degradation and loss to prevent harmful side effects and to increase bioavailability. Based on the physical and biochemical mechanism, novel drug delivery is designed. The present review gives information regarding various novel techniques to target therapeutic efficacy. Targeting can be achieved by delivering drug to the site of interest via drug carriers. Drug carriers are formed of soluble polymers and the micro particles are made of insoluble or biodegradable natural or synthetic polymers, nanoparticles, liposomes. Hence, Novel Drug Delivery will help to overcome various issues. KEYWORDS: Novel Drug Delivery System, Drug targeting delivery system, liposome, Nanoparticles, Noisome, Hydrogels. 1. INTRODUCTION: - 1.1 Novel drug delivery system: Novel drug delivery system has opened a new gate for the researchers in the field of science where materials in Nano scale range are employed to serve as a diagnostic tool to deliver drug or agents to specific target sites in a controlled manner. Novel drug delivery has not only helped to suppress conventional dosage form but also rebuilt new strategies to overcome its toxicity and side effects caused by it. Novel Drug Delivery Systems has captured interest in both national and international pharmaceutical research organization. It is an expression associated to enhance the performance of bio therapeutic agents when compared to conventional dosage form.