. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Abstract citation ID: dead093.213 O-176 Knowledge and belief about fertility preservation for medical and social reasons among Iranian female students F. Ranjbar 1 , M.M. Akhondi 2 , Z. Behjati Ardakani 3 , J.C. Warmelink 4 , S. Haghani 1 1 Iran University of Medical Sciences, Nursing and Midwifery Care Research Center, Tehran, Iran 2 Avicenna Research Institute- ACECR, Reproductive Biotechnology Research Center, Tehran, Iran 3 Islamic Azad University- Central Tehran Branch, Department of Sociology, Tehran, Iran 4 AVAG- University Medical Center Groningen- University of Groningen, Department of General Practice and Elderly Care Medicine- Section Midwifery Science, Groningen, The Netherlands Study question: What is the knowledge and beliefs of the female students in Tehran universities regarding the oocyte cryopreservation for medical and social reasons? Summary answer: This study highlighted the positive attitude but insuffi- cient knowledge about medical and social egg freezing and the ideal timing of childbearing in female students. What is known already: Emerging research indicates that physiologic or pathologic ovarian aging limits the female reproductive capacity and oocyte cryopreservation (OC) is a rapidly evolving branch of reproductive medicine. Given the growing numbers of young women surviving cancer, along with in- creasing numbers of high educated women postponing childbearing for educational or professional pursuits, there will be a growing demand for egg freezing services to guarantee the pregnancy in near future. Egg freezing can prevent age-related infertility, but it also can cause new potentially ethical and financial problems and the neonatal and maternal risks of childbearing at an advanced maternal age. Study design, size, duration: Totally, 1279 students from Tehran universi- ties were included in this cross-sectional survey between March and August 2022. Participants/materials, setting, methods: The survey was distributed through an online forum and advertised on social media groups targeting stu- dents in Tehran universities. Childless students in master’s and doctoral degrees with the age of  38 years were included. Bachelor’s students were not included. Knowledge and beliefs about medical and non-medical oocyte cryopreservation were assessed through Fertility Preservation Survey (FPS) in- strument. To analyze the data, descriptive statistical methods (mean and standard deviation) and analytical statistics (One-way ANOVA) were used. Main results and the role of chance: The majority of participants were 30-34 years (41.1%, M: 26.38 § 4.9), not married (77.2%), master’s student (77.7%), and hoped to have 2 children in the future (40.5%). Most of partici- pants expected to be “30-34 years” when they become pregnant with their first child (34.4%) and “35-39 years” when they give birth to their last child (39.1%). The students agreed with preserving fertility with medical (93.3%) and social (86.9%) indications and believed medical (95.1%) and social (87.4%) costs of cryopreservation should be covered by health system. Participants believed in the routine providing of information about egg freezing to women of childbearing age as part of regular healthcare visits by health care professionals (95.5%). Women stated if they decide not to use eggs to become pregnant, they would consider donating them for fertility research (67.1%), to a friend or family member with fertility problems (58.1 %) and to infertile couples (42.7%). The overall correct response to knowledge ques- tions was 57.7% which is relatively moderate. The marital status (P ¼ 0.028), university faculty (P ¼ 0.025) and occupation (P ¼ 0.048) were related to knowledge. Married (M: 7.40 § 1.98) and unemployed students (M: 7.24 § 2.24) had more knowledge and students of Art faculty had lower knowledge than other faculties (M: 6.36 § 2.22). Limitations, reasons for caution: The results would not be generalizable to all female students because the research project’s advertisement may have been ignored by students who are not interested in childbearing or it might have been noticed by students who are more interested in childbearing and preserving their fertility. Wider implications of the findings: The findings are valuable in planning fertility preservation services. The supportive policies for childbearing could be expanded to cover the costs of fertility preservation. Midwives could play an important role in increasing the knowledge about age-related infertility and oocyte cryopreservation and help students in their reproductive life planning. Trial registration number: not applicable Abstract citation ID: dead093.214 O-177 The importance of an onco-fertility program for pediatric oncology patients I. IJgosse 1 , L. Looijenga 2 , A. Klijn 3 , R. Oude Ophuis 4 , M. Heuvel- Eibrink van den 5 , M. Veening 6 , A. Bos 7 , S. Broer 7 , J. Leeuwen van 8 , L. Steeg van der 9 , S. Sriram 2 , M. Perk van der 2 , M. Wetering van de 1 1 Princess Maxima Centre, Pediatric oncology- Quality of life, Utrecht, The Netherlands 2 Princess Maxima Centre, Research, Utrecht, The Netherlands 3 UMCUtrecht, Pediatric Urology, Utrecht, The Netherlands 4 UMCUtrecht, Fertility- clinical embryology, Utrecht, The Netherlands 5 Princess Maxima Centre, Pediatric oncology- solid tumors, Utrecht, The Netherlands 6 Princess Maxima Centre, Pediatric oncology- hemato oncology, utrecht, The Netherlands 7 UMCUtrecht, Gynaecology- fertility, Utrecht, The Netherlands 8 UMCUtrecht, Gynaecology- pediatric gynaecology, Utrecht, The Netherlands 9 Princess Maxima Centre, Pediatric surgery, Utrecht, The Netherlands Study question: How to start an onco-fertility program in a pediatric oncol- ogy unit as standard of care Summary answer: An active onco-fertility program helps to offer the best option for future fertility for pediatric oncology patients. Awareness of fertility risk is necessary. What is known already: Infertility after treatment for pediatric oncology is an important late effect Of these patients, 25-35 % classify as high risk (HR) for infertility. With the increasing survival chance (>80%) this late effect plays an important role. Study design, size, duration: An onco-fertility program was started in 2018 with the start of a centralized hospital for pediatric oncology patients (yearly 600 patients) navigated by a nurse-practitioner. The program runs with intense collaboration between the different specialties. All new patients are identified. Fertility-risk is based on the international fertility guidelines. Participants/materials, setting, methods: All patients are informed on fertility risk by their oncologist. All HR children are additionally counseled by the onco-fertility nurse-practitioner and referred for further counseling to gy- necology for ovarian tissue cryopreservation(OTC) or urology for sperm cryopreservation or testicular biopsy (in research setting). Monthly the onco- fertility working-group members discuss difficult cases and research in the field. Survivors have the possibility for fertility consultations. Main results and the role of chance: Awareness of treatment (chemo- therapy, radiotherapy and surgery) on fertility in children has increased from 2018 till now 2023 among oncologists, nursing staff, carers of the child, and the patients themselves. We offer fertility preservation mainly in the high risk for infertility group but also for low risk groups we offer information and counseling . In the outpatient clinic for survivors, there is an increasing num- ber of consults yearly on fertility questions From 2018 till 2022 we saw a fourfold of consults. The number of high risk for infertility over the years is stable around 30%. Over the years we see an increasing number of patients who have fertility preservation done in time In the girls this increased from 32% in 2018 to nearly 40% in 2022. For the boys it increased from 37% in 2018 to 57% in 2022 Limitations, reasons for caution: This is an ongoing programme in a large pediatric oncology unit in a first world country where this programme is pos- sible. insurance is well organized We realize that in other countries it is much more difficult to run this program 39 th Hybrid Annual Meeting of the ESHRE, Copenhagen – Denmark, 25-28 June 2023 i107 Downloaded from https://academic.oup.com/humrep/article/38/Supplement_1/dead093.213/7202873 by guest on 24 June 2023