Akhilesh Gupta et al, Int. Journal of Pharmaceutical Sciences and Medicine (IJPSM), Vol.6 Issue. 12, December- 2021, pg. 29-38 ISSN: 2519-9889 Impact Factor: 5.365 © 2021, IJPSM All Rights Reserved, https://ijpsm.com/ 29 Ageratina Adenophora Plant: A Review – One Plant with Many Therapeutic Uses Akhilesh Gupta*; Vivek Gupta 1 Monad University N.H. 9, Delhi Hapur Road Village & Post Kastla, Kasmabad, Pilkhuwa, Uttar Pradesh Corresponding Author: Akhilesh Gupta* E-mail: pharmaakhilesh1125@gmail.com DOI: 10.47760/ijpsm.2021.v06i12.003 ABSTRACT: Ageratina adenophora, often known as Crofton Weed, is one of the common invasive weeds which first originated from Mexico and Central America and gradually invaded numerous parts of the world. Because of it stability to alter the soil microbial communities and its allelopathic competition with other plant species, this plant colonizes forest margins, stream banks and disturbed areas in large dense clumps and is found to possess potent toxicological effects on livestock; the lethal chronic pulmonary disease has been reported in horses while liver complications have been reported in mice. Despite this, the plant has been studied more extensively for its therapeutic uses as phytochemicals viz. steroids, tannins, triterpenes, coumarins and saponins(7-hydroxy-dehydrotremetone,7,10,11-trihydroxy-dehydrotremetone,10- oxo-7-hydroxynordehydro-tremetone,Eupatorone,2-deoxo-2-(acetyloxy)-9- oxoageraphorone(DAOA), 9-oxoagerophorone(OA), etc.) which have been reported are found to possess antimicrobial activity, antipyretic activity, wound healing, antioxidant activity, analgesic activity, anti-tumor activity, insecticidal activity, antiviral activity, anti-inflammatory activity, larvicidal activity. This present review is an effort to give a detailed survey of the literature on invasive nature, pharmacological study, phytochemical review, and ethno botanical and therapeutically uses of the plant A. adenophora, which could help researchers for advanced qualitative research on it. Keywords: Ageratina adenophora, Crofton weed, Pharmacological, Invasive, Phytochemical INTRODUCTION: Ageratina adenophora (Spreng.) (adenophora = ‘aden’ (a gland) + ‘phoros’(bearing);refers to oil-producing glands in the leaves), one of the species of the Asteraceae family is a perennial, semi-shrubby herbaceous plant which grows up to 3m tall in moist conditions, such as on the edges of slow-flowing streams in waterlogged soaks, on steep slopes and in high rainfall areas Catweed, hamp agrimony, Maui pāmakani, pāmakanihaole, etc.), is named after the councilor in Lismore Shire, New South Wales, Australia, when the species first became identified as an invasive weed 1 .