Türkler C, Ulug P, Uzel K, Kurnuc FZ, Sayar I et al./Aegean J Obstet Gynecol 4/1 (2022) page 19-21 19 Aegean Journal of Obstetrics and Gynecology 4/1 Aegean Journal of Obstetrics and Gynecology Case Report Twin pregnancies with complete hydatidiform mole: A case report Can Türkler a, , , Pasa Ulug a, , Kemine Uzel b, , Fatma Zehra Kurnuc a, , Ilyas Sayar c, , Diren Vuslat Çagatay c, a DeparWmenW of G\necolog\ and ObsWeWrics, Er]incan Binali Yﾕldﾕrﾕm UniYersiW\ FacXlW\ of Medicine, Er]incan, Turkey b Department of Gynecology and Obstetrics, Mengücek Gazi Training and Research Hospital, Erzincan, Turkey c DeparWmenW of PaWholog\, Er]incan Binali Yﾕldﾕrﾕm University Faculty of Medicine, Erzincan, Turkey A B S T R A C T Objective: The association between twin pregnancies and hydatidiform mole is a rare clinical condition. With the development of ultrasonography devices, prenatal diagnosis has become easier. Case Report: A 21-year-old patient with gravidity 1 parity 0 applied to our clinic with the complaint of vaginal bleeding at week 16 of her pregnancy according to her last menstrual period. A pregnancy termination option was offered to the patient who was diagnosed with twin pregnancy consisting of a complete hydatidiform mole and a co- existent fetus as a result of the examinations and tests. Emergency laparotomy was planned for the patient who did not accept the pregnancy termination option due to severe vaginal bleeding at week 21 of pregnancy. Conclusion: Although live births are reported in the literature in cases where twin pregnancy and hydatidiform mole are seen together, pregnancy termination due to vaginal bleeding may be required in earlier weeks. Keywords: hydatidiform mole; hysterectomy; twin pregnancy; ultrasound; vaginal bleeding A R T I C L E I N F O Doi: 10.46328/aejog.v4i1.97 Article history: Received: 10 October 2021 Revision received 08 December 2021 Accepted 28 December 2021 © 2022 AEJOG Introduction Hydatidiform mole is a rare pregnancy complication, however it can turn into forms that require systemic or surgical treatment. Hydatidiform mole has two histopathological subgroups: partial (PM) and complete mole (CM) [1]. Twin pregnancy consisting of a complete hydatidiform mole and a co-existent fetus (CHMF) is rare clinical condition [2]. The incidence of this clinical situation ranges from 1 22.000 to 1 in 100.000 pregnancies [3]. The presented case was followed up with the diagnosis of abortus imminens in an external health center until the 16th gestational week and admitted to our clinic with complaint of vaginal spotting. Transabdominal ultrasound examination revealed a pregnancy of 16 weeks gestation with live fetus. One of the placentae was separate and the sonoluscent areas were interpreted as molar tissues at the level of the uterine isthmus. This case reported aimed to share this rare condition and our clinical experiences gained from this case. Case Report A 21-year-old patient with gravidity 1 parity 0 applied to our clinic with complaint of vaginal bleeding at week 16 of her pregnancy according to her last menstrual period. The patient was followed up by another center with the diagnosis In the ultrasonographic examination, a live and anatomically normal fetus compatible with 16 weeks of pregnancy was observed. Also, a normal placenta observed on the anterior wall of the uterus and a 7.5 x 12-cm-molar placental tissue at the level of the uterus isthmus were observed accompanying a single fetus in a single amniotic cavity (Figure-1). Figure 1: Ultrasonographic images of the case. The patient was hospitalized with the preliminary diagnoses of partial mole and CHMF. In the examinations performed, maWernal serXm ǃ hXman chorionic gonadoWropin (MS-ǃhCG) was found to be 340,000 mIU / mL, thyroid-stimulating hormone (TSH) 0.01 µU / mL, and free thyroxine (T4) 1.11 ng / dL. Other laboratory values were found to be within limits.  Corresponding author. E-mail: dr_canturkler@yahoo.com Orcıd Id; 0000-0003-2716-0322