Accepted Manuscript Design, synthesis, in vivo and in silico evaluation of phenacyl triazole hydra- zones as new anticonvulsant agents Leila Dehestani, Nematollah Ahangar, Seyedeh Mahdieh Hashemi, Hamid Irannejad, Patrick Honarchian Masihi, Aidin Shakiba, Saeed Emami PII: S0045-2068(17)30875-1 DOI: https://doi.org/10.1016/j.bioorg.2018.03.001 Reference: YBIOO 2291 To appear in: Bioorganic Chemistry Received Date: 19 November 2017 Revised Date: 28 February 2018 Accepted Date: 2 March 2018 Please cite this article as: L. Dehestani, N. Ahangar, S. Mahdieh Hashemi, H. Irannejad, P. Honarchian Masihi, A. Shakiba, S. Emami, Design, synthesis, in vivo and in silico evaluation of phenacyl triazole hydrazones as new anticonvulsant agents, Bioorganic Chemistry (2018), doi: https://doi.org/10.1016/j.bioorg.2018.03.001 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.