Material and Methods: We conducted a prospective research approved by the Ethics Committee of our center, using the Supportive Care Needs Survey Short Form 34 (SCNS SF 34). The study period was from December 2015 to November 2016. We proposed the study to newly diagnosed patients. We asked them to answer SCNS SF 34 the 1st month and the 6th month after the diagnosis. We compared the results between these two periods and analyzed which social, personal, health, diagnostic and treatment factors could significantly influence the results of the test. We used Wilcoxon or Man-Whitney tests when necessary. Results: During the study period we treated 214 patients in our Breast Unit: 101 accepted to participate in the study. Of these, 65 eventually answered the test the 1st month and 22 the 6th month. Unmet needs tended to diminish the first six months after the diagnosis, but the difference was not significant (p = 0.077). The highest scores were for psychological needs in both periods. We detected significantly higher needs for patients with self- rated poor health affecting the overall result of the test and the psychological, physical, sexuality and relation with the health system areas, either on the 1st and the 6th month. Sexual needs were higher for patients <50 years old in the 1st month period. Needs for self-care counseling in the 6th month were lower for patients with acquaintances who had already been treated for a breast cancer. Conclusion: In our setting, general needs decreased the first six months after the diagnosis, but the psychological needs remained high. Some patient features, as self-perceived poor health and age, modified the pattern of unmet needs. Of note, the study suggested that being able to contact an expert patient lowered some specific unmet needs. This finding will enable us to design specific interventions and improve our patients’ quality of life during treatment. No conflict of interest 156 (PB-057) Poster Pulmonary complications in breast cancer survivors: Long-term effects of adjuvant treatment? S. Siesling 1,2 , S. Abbas 2 , J. Van der Palen 3,4 , P. Van der Valk 5 , M. Heuvelmans 5,6 , H. Heijmans 7 , J. Jobsen 8 , H. Struikmans 9 . 1 Netherlands Comprehensive Cancer Organisation IKNL, Research, Enschede, Netherlands; 2 University of Twente, Health Technology and Services Research, Enschede, Netherlands; 3 University of Twente, Research Methodology, Measurements and Data Analysis, Enschede, Netherlands; 4 Medisch Spectrum Twente, Clinical Epidemiology, Enschede, Netherlands; 5 Medisch Spectrum Twente, Pulmonology, Enschede, Netherlands; 6 University Medical Center Groningen, Center for Medical Imaging – North East Netherlands, Groningen, Netherlands; 7 Ziekenhuisgroep Twente, Surgery, Hengelo, Netherlands; 8 Medisch Spectrum Twente, Radiotherapy, Enschede, Netherlands; 9 Leiden University Medical Center, Radiotherapy, Leiden, Netherlands Background: Breast cancer patients are frequently treated with a combina- tion of surgery, radiotherapy, chemotherapy, and/or hormonal therapy. These treatments may cause early and late side effects. Since survival for breast cancer patients is increasing, due to early detection and improved treatment strategies, it is important to study the late side effects. Since the ipsilateral lung receives radiation dose as well, pulmonary complications can be expected. However, knowledge on long-term pulmonary side-effects is limited. Aim of this study was to determine the long-term (10–20 years) pulmonary complications/side-effects in women, treated with breast-con- serving surgery, radiotherapy and/or adjuvant systemic therapy. Material and Methods: Fifty-three women, aged 39–75 years, treated with breast conserving surgery for early stage breast cancer between 1996 and 2006 were included. Primarily breast-conserving surgery was followed by loco-regional radiotherapy with or without adjuvant chemotherapy and/or hormonal therapy. Patients had survived at least ten years. Data on pulmonary complications ( pneumonitis, pulmonary fibrosis) and factors that might influence the risk of pulmonary complications (i.e. smoking) were obtained retrospectively. A Cohens-kappa was used to determine the relation between laterality of the irradiated side as well as the laterality (if applicable) lung side where the pulmonary complication was diagnosed. A Kaplan-Meier analysis was used to determine the effect of smoking and the time until pneumonitis or pulmonary fibrosis after treatment. Results: Mean patient age at start of treatment was 58 years (SD 9.3). Pulmonary complications were noted in 24 patients (45%) (Table 1). In all cases, pneumonitis or pulmonary fibrosis developed in lobes of the ipsilateral irradiated breast side ( p < 0.001). Between smoking (yes/no) and the development of pneumonitis ( p = 0.195) or pulmonary fibrosis ( p = 0.273) no statistically significance was found. Alcohol consumption, BMI and age were not significantly associated with development of pneumonitis or pulmonary fibrosis. Table 1 Distribution of late effects per irradiated breast side and smoking status (n = 53) All patients N (%) Treated side N (%) Smoker N (%) Non-smoker N (%) Unknown smoking status N (%) Pneumonitis 4 (7.5%) 4 (100%) 2 (25%) 2 (25%) 4 (50%) Pulmonary fibrosis 12 (22.6%) 12(100%) 2 (13%) 7 (44%) 7 (44%) Pneumonitis & Pulmonary fibrosis 4 (7.5%) 4 (100%) Conclusion: We noted, in a limited sized cohort of 53 breast cancer patients, a strong relation between the loco-regional irradiated breast side and the side of pneumonitis and pulmonary fibrosis. We found no other significant factors being associated with the development of pulmonary complications. No conflict of interest 157 (PB-058) Poster Effect of sleeve application for lymphoedema on Quality of Life (QoL) and arm volume swelling (results of prospective BEA study) N. Bundred 1 , L. Edmond 2 , P. Foden 2 , K. Riches 3 , J. Morris 2 , A. Evans 4 , C. Todd 2 , M. Bramley 5 , A. Skene 6 , T. Hodgkiss 5 , P. Arnie 7 , V. Keeley 3 . 1 University Hospital of South Manchester NHS Foundation Trust, Academic Surgery, Manchester, United Kingdom; 2 The University of Manchester, Faculty of Biology, Medicine and Health, Manchester, United Kingdom; 3 Derby Hospitals NHS Foundation Trust, Lymphoedema, Derby, United Kingdom; 4 Poole Hospital NHS Foundation Trust, Breast Surgery, Poole, United Kingdom; 5 Pennine Actue Hospitals NHS Trust, Breast Cancer, Manchester, United Kingdom; 6 Royal Bournemouth & Christchurch Hospitals NHS Foundation Trust, Specialist Breast Cancer Unit, Bournemouth, United Kingdom; 7 Guy’s & St Thomas’ NHS Foundation Trust, Breast Surgery, London, United Kingdom; On behalf of The Investigators of the Bea Study Background: Application of an external compression sleeve is recom- mended to treat lymphoedema (defined by Relative Arm Volume Increase (RAVI) > 10%). Material and Methods: In a prospective NIHR study (UKCRN ID 8881), 1,100 patients undergoing axillary clearance, had pre-operative and post- surgery arm measurements by perometry, Bioimpedance (BIS (L-Dex)) and provided, FACT-B + 4 and lymphoedema checklist questionnaires. RAVI of >10% diagnosed lymphoedema. By 24 months post-surgery 219 (21.1%) patients received compression sleeve application. To determine patients benefiting from sleeve application, RAVI, QoL and self-reported changes were related to effects of treatment on QoL. Changes in QoL were analysed using GEE. The FACT-B + 4 summary scores and the Table (abstract 157 PB-058). GEE:Estimated marginal mean (95% CI) N Pre surgery Before sleeve applied At sleeve application At 36 months P value Total Fact B + 4 214 106.9 (104.1–109.7) 103.6 (100.5–106.5) 105.0 (102.0–107.9) 108.5 (104.8–111.9) 0.001 ARM 212 18.7 (18.3–19.0) 15.4 (14.8–15.9) 14.2 (13.6–14.8) 15.2 (14.4–15.8) <0.001 TOI 214 66.7 (64.7–68.6) 62.7 (60.6–64.7) 63.6 (61.5–65.7) 66.8 (64.3–69.3) <0.001 European Journal of Cancer 92, Suppl. 3 (2018) S17–S160 S36 Abstracts, EBCC 11 Poster Session (Wednesday, 21 March 2018)