Original Article STUDY THE LEVEL OF AWARENESS AMONG SINDHI FAMILIES OF DURG, CHHATTISGARH (INDIA): A QUESTIONNAIRE BASED STATISTICAL STUDY SAPNA THAKUR, SHARADA NANDAN RAW, RAVINDRA SHARMA Department of Mathematics, National Institute of Technology Raipur, India Email: sapnarajput85@gmail.com Received: 19 Mar 2015 Revised and Accepted: 17 Jul 2015 ABSTRACT Objective. The present study has been done with the following aims and objectives in mind: i) To determine the level of knowledge or awareness about Thalassemia among Sindhi families in Durg, Chhattisgarh regarding the cause and prevention of the disease and ii) graphically represents their status of awareness. Methods. In this study, we have used a questionnaire method which is done among 12 Sindhi families and determined their response rate about Thalassemia. Data are collected by survey in Durg districts of Chhattisgarh that targeted Thalassemic Sindhi families, they are the members of Thalassemia Welfare Society (TWS), Raipur (Capital of Chhattisgarh)- it’s an affiliated organization. We have examined the attitudes regarding management of Thalassemia disease (TD) through their responses against questionnaire and represented their responses using MATLAB 8.4. Results. In our study, we have found that overall, 64.91% participants are females and 35.09% are males. Also 20% of respondents felt comfortable with the questionnaire method of TD. The frequencies of reactions were 20%, giving the right answers and 28%, giving wrong answers while half is not thinking about the given questionnaire. Conclusions. We have obtained the knowledge level among Sindhi families is very poor about TD. Therefore variousprevention policies are must be organized to increase their knowledge about Thalassemia and improve Thalassemic children'ssurvival capability. Keywords: Durg district of Chhattisgarh, Genetic disease burden, Knowledge about Thalassemia, Sindhi families, Thalassemia. INTRODUCTON Our genes are the directions for how our bodies function. We get 50% of our genes or qualities from our mothers and half from our fathers, making for two duplicates of each quality (gene) in our body. People with Thalassemia disease are conceived with it. It is not infectious, and you can't get Thalassemia disease from somebody who has it. It is in our genes. The main path for somebody to have Thalassemia illness is to have inherited one quality for their red platelets that is not living up to expectations from their mother, and one non-meeting expectation quality of their father. Individuals with Thalassemia disease have inherited two qualities that are not meeting expectations appropriately. Thalassemia major is a severe form of Thalassemia in which patient needs lifetime blood transfusion and appropriate medication [1]. Thalassemia major patients are diagnosed on the premise of history and hemoglobin–Electrophoresis (it is a test to distinguish the sorts of hemoglobin chains in a single person. The chains are sorted by size and electrical charge utilizing differential relocation through a gel) with evaluation of HbF and HbA 2 by High-Performance Liquid Chromatography (HPLC). Thalassemia disease requires a significant degree of medical involvement, and family members are one potential provider of care for patients who do not have access to experts. Therefore, it is required for the parents of Thalassemia children, to have adequate knowledge about Thalassemia management. The objective of this study is to focus the knowledge level of Thalassemia disease (TD) among Sindhi families at their homes in Chhattisgarh, a state spotted in the central part of India. In this study, we use a questionnaire method which is done among 12 Sindhi families and determined their knowledge level, attitudes and beliefs of the participants about TD. Since the frequency of Beta-Thalassemia among different groups is higher, it is roughly 3 to 17 percent in India [2-4]. According to the screened population of Chhattisgarh [5] Thalassemia trait in the screened population is approximately 10 percent where the frequency of the Thalassemia Gene (TG) is higher among Sindhi families. Treatments for Thalassemia major patients impose a budgetary trouble in the family. The remaining part of this paper is organized as follows: The prevalence of genetic diseases is explained in Introduction section and the date of questionnaire method is shown in Materials and Methods section. A response rate of the questionnaire is graphically represented in Result section. Discussion about the responses of the questionnaire and interview are considered in Discussion section and the conclusion section gives an output of the study. Prevalence of genetic diseases in Chhattisgarh between different communities Thalassemia and other hemoglobin disorders like sickle cell hemoglobin [6] are reported to be common in central India, especially in Chhattisgarh and Madhya Pradesh. Sickle cell disease (SCD) is an autosomal dominant hemoglobinopathy. Chhattisgarh is the 26 th state of India, which came into existence on 1 st November 2000. Sickle cell infection (SCD) makes a rising well being issue in different population groups of Chhattisgarh. The associated fig. 1, shows to the spreading of sickle cell disorders, β-Thalassemia trait, and the glucose-6-phosphate dehydrogenase (G6PD) enzyme deficiency in four tribes of Chhattisgarh and Orissa [7] where Thalassemia and G6PD are the form of genetic disorders. Fig. 1: Prevalence of SCD, Beta-Thalassemia trait and G6PD deficiency in Chhattisgarh, India International Journal of Pharmacy and Pharmaceutical Sciences ISSN- 0975-1491 Vol 7, Issue 9, 2015 Innovare Academic Sciences