165 www.pediatriadanas.com We report a case of a 16-year-old girl with hyaline-vascular type of abdominal Castleman’s disease. The patient presented with a history of palpable mass below left ribcage for 6 months. On admission the girl was in good general condition. Physical exami- nation showed a palpable mass in the left hemiabdomen but was otherwise unremarkable. Laboratory fndings were within normal limits except hypergammaglobulinemia with elevated immuno- globulin A level. Computed tomography (CT) revealed well-de- marcated homogeneous mass, extending from left diaphragm to the lower pole of left kidney, as well as from peritoneum to the pancreas. CT-guided biopsy was performed. A biopsy material was considered insuffcient for defnitive diagnosis. A complete surgical resection was done, and a diagnosis of hyaline-vascu- lar type of Castleman’s disease was established. Eight years af- ter surgery the patient is in complete remission. Conclusion - Castleman’s disease is a rare benign lymphoproliferative disor- der, whose early recognition can be diffcult due to nonspecifc symptoms and radiologic fndings. The right pathohistological diagnosis and appropriate staging of the disease are crucial in the treatment planning. Key words: Castleman’s disease ▪ Lymphoproliferative disorder ▪ Child Introduction Castleman’s disease (CD) is a benign lymphoproliferative disorder, with unknown aetiology. There are localized or unicentric and systemic or multicentric forms. CD most often presents as a solitary soft tissue mass in the media- stinum, and may be located extra-thoratically: in the neck, Case report Jelena ROGANOVIĆ 1 , Petra ĆOZA 1 , Nives JONJIĆ 2 CASTLEMAN’S DISEASE – CASE REPORT 1 Department of Pediatrics Clinical Hospital Center Rieka Republic of Croatia, 2 Department of Pathology School of Medicine University of Rieka Republic of Croatia Jelena Roganović Department of Pediatrics Clinical Hospital Center Rieka Istarska 43 HR - 51000 Rieka Republic of Croatia jelena.roganovic1@ri.t-com.hr Tel.: + 385 51 659 103/109 Fax.: + 385 51 623 126 Received: August 8, 2012 Accepted: September 22, 2012 Copyright © 2012 by University Clinical Center Tuzla. E-mail for permission to publish: paediatricstoday@ukctuzla.ba Paediatrics Today 2012;8(2):165-171 DOI 10.5457/p2005-114.53