SM Journal of Food and Nutritional Disorders Gr up SM How to cite this article Trivedi MK and Jana S. Transformation of the Physico-Chemical, Thermal, and Behavioral Properties of Tetrahydrocurcumin by means of the Consciousness Energy Healing Treatment. SM J Food Nutri Disord. 2019; 5(1): 1024. OPEN ACCESS ISSN: 2573-3664 Introduction Tetrahydrocurcumin (THC) is a colorless or white polyphenolic metabolite of curcumin and quite similar physiological and pharmacological properties of curcumin [1,2]. In contrast, THC showed the strongest antioxidant activity than the other naturally-occurring curcuminoids, including curcumin, demethoxycurcumin, and bisdemethoxycurcumin [2-5]. It has diferent molecular targets, signaling pathways, cellular responses, and clinically more advantageous compared with the curcumin [2-5]. Many studies reported that THC has signifcant results in preventing infammation, hepatotoxicity, nephrotoxicity, cancer, diabetes, rheumatoid arthritis, the ageing process, atherosclerotic lesions treatment, etc. [2-7]. However, THC does not have toxicity even at higher doses and can be used against tumors of the skin, colon, pancreas, breast, and other skin diseases like psoriasis, and scleroderma. [5,7]. THC plays a notable role in angiogenesis and also improves the accumulation of extracellular matrix (ECM) components through the remodeling of the wound repair [5]. Te chemical structure of the THC is found in two diferent forms, such as diketo and keto-enol tautomeric form (Figure 1) [8]. Te degradation half-lives of THC is 813 minutes in cell culture medium and 232 min in plasma [2]. However, many studies conducted on the bioavailability of THC and was found better bioavailable in the intestine, hepatic cytosol, brain, etc. compared to the curcumin but neither THC nor curcumin was detected in the plasma of mice [9]. Better bioavailability in the animal body is the major issue for THC. Te Biofeld Energy Treatment (the Trivedi Efect®) could be an economical approach for the reduction of particle size and improvement of the surface area; hence the bioavailability of THC can be increased [10,11]. Te human body can discharge the electromagnetic waves in the form of bio-photons that surrounds the body. Tis electromagnetic energy is generated by the continuous movement of the electrically charged particles (ions, cells, etc.) inside the body. Tis energy is collectively known as “Biofeld Energy”. Biofeld Energy Healing practitioners have the ability to harness the energy from the “Universal Energy Field” and can transmit into any living or non-living object(s) around the earth. Te process, where the objects receive the Biofeld Energy Treatment and respond into Research Article Transformation of the Physico-Chemical, Termal, and Behavioral Properties of Tetrahydrocurcumin by means of the Consciousness Energy Healing Treatment Mahendra Kumar Trivedi 1 and Snehasis Jana 2* 1 Trivedi Global, Inc., USA 2 Trivedi Science Research Laboratory Pvt. Ltd., India Article Information Received date: Aug 30, 2019 Accepted date: Nov 01, 2019 Published date: Nov 04, 2019 *Corresponding author Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Thane (W), Maharashtra, India Tel: +91- 022-25811234 Email: publication@trivedieffect.com Distributed under Creative Commons CC-BY 4.0 Keywords Tetrahydrocurcumin; The Trivedi Effect ® ; Biofeld energy; Consciousness energy healing treatment; PXRD; Particle size; DSC; TGA/DTG Abstract Tetrahydrocurcumin (THC) is a major metabolite of curcumin used as an antioxidant, anti-infammatory, antiarthritic, anticancer, etc. The objective of this study was to evaluate the impact of the Trivedi Effect ® - Biofeld Energy Healing Treatment on the physicochemical, thermal, and behavioral properties of THC using sophisticated analytical techniques. The test sample was divided into two parts, one part of THC was considered as a control sample, while another part received the Biofeld Energy Healing Treatment remotely by a famous Biofeld Energy Healer, Mr. Mahendra Kumar Trivedi. The PXRD data showed that the THC was crystalline in nature. The relative peak intensities and crystallite sizes of the Biofeld Energy Treated sample were signifcantly altered ranging from -17.76% to 17.20% and -26.68% to 326.39%, respectively compared to the control sample. However, the average crystallite size of the treated THC was decreased by 2.50% compared with the control sample. The particle size values of the treated sample were signifcantly decreased by 11.58% (d 10 ), 14.41% (d 50 ), 15.53% (d 90 ), and 15.23% {D(4,3)} compared with the control sample. Thus, the surface area of the treated sample was signifcantly increased by 14.24% compared with the control sample. The melting point and latent heat of fusion were decreased by 0.40% and 0.70%, respectively, in the treated sample compared to the control sample. The weight loss and maximum thermal degradation temperature in the treated THC were decreased by 0.62% and 1.54%, respectively compared with the control sample. Overall, the thermal analysis indicated that the thermal stability of the Biofeld Energy Treated THC was declined compared to the control sample. The Trivedi Effect ® -Consciousness Energy Healing Treatment might lead to the production of a new polymorphic form of THC, which would be more soluble and bioavailable compared with the untreated THC. The Treated THC would be very useful to design more effcacious nutraceutical/pharmaceutical formulations against the infammatory diseases, arthritis, cancer, diabetes, hepatotoxicity, nephrotoxicity, etc.