This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/cge.13857 Title: Age of Onset and Behavioral Manifestations in Huntington’s Disease: An Enroll-HD Cohort Analysis Authors: Megha Ranganathan, MS, CGC 1,2 Sandra K. Kostyk, MD, PhD 3* Dawn C. Allain, MS, LGC 1 Jonathan A. Race, PhD 4,5 Allison M. Daley, MS, MPH, LGC 3 1 Division of Human Genetics, Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA 2 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA (current address) 3 Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA 4 Division of Biostatistics, The Ohio State University, Columbus, OH, USA 5 Eli Lilly and Company, Indianapolis, IN (current address) Word count: 5988 Key words: Huntington’s disease, behavior, age of onset, phenotype Running title: Age of Onset and Behavioral Symptoms in HD Figures and tables: 7 Corresponding Author: *Sandra K. Kostyk, MD, PhD The Ohio State University 395 W. 12 th Ave. Columbus OH 43210 USA Phone: 001-614-293-4969 Fax: 001-614-293-6111 sandra.kostyk@osumc.edu This article is protected by copyright. All rights reserved.