ABSTRACT Background and O bjectives: The present study was conducted to assess the effects of low dose Midazolam with Propofol and Propofol alone during minor oral and maxillofacial surgeries; to evaluate the level of sedation, post-operative amnesia, and condition of the patient during surgery, patient satisfaction and opinion. Material and Methods: Fifty ASA G rade I and II patients were rando mly allo cated into two equal gro ups (n = 25 in each). The Propofol group, received Propofol bolus of 0.7mg/kg and the Midazolam + Pro po fo l g ro up received a low dose Midazolam bolus of 0.03mg/kg prior to Propofol bolus of 0.7mg/kg. Propofol continuous infusio n o f 50 micro gram/ kg/ min was given after the bo lus in bo th the gro ups. Results: The level of sedation was better in the Midazolam + Propofol during the operative procedure. Patient condition was rated excellent during the operative procedure in 72% patients in the Midazolam + Propofol group and 60% patients in the Propofol group by the surgeon. The level of amnesia was greater in Midazolam + Propofol group and statistically significant. 80% patients in the Midazolam + Propofol group and 48 % in the propofol alone group were well satisfied with the sedation techniques. Conclusion: The addition of low dose Midazolam to Propofol is a good and safe option for conscious sedation in minor O ral and Maxillofacial Surgeries as it produces superior quality sedation without serious complications. Key words: Conscious sedation; Intravenous sedation; Propofol; Midazolam; Amnesia INTRODUCTION The management of fear and apprehension on the part of the patient undergoing surgery has been an integral part of patient management. Several minor surgical procedures performed under local anesthesia, subject the patient to a rather unpleasant experience. General anesthesia on the other hand demands a more specialized operatory setup, accurate monitoring and increases treatment cost. The possibility of anesthetic complications would be another cardinal drawback of general anesthesia. The administration of local anesthetic is considered to be a traumatic procedure by most patients, and hence incites a fear of pain amongst them, [1, 2, 3, 4] producing fear and apprehension. These apprehensive patients can therefore be managed by inducing an altered state of consciousness in which a person is more relaxed and carefree than previously. Original Research ADDRESS FOR CORRESSPONDENCE: Dr.Mohammad Ali R Patel, MDS Assistant Professor Department of Dentistry KBN Institute of Medical Sciences Gulbarga, Karnataka Email ID: dr.ali_omfs@yahoo.com MAHARAJA KRISHNAKUMARSINHJI BHAVNAGAR UNIVERSITY 50 Vol. 4 Issue-1 January 2014 *Assistant Professor, Department of Dentistry, KBN Institute of Medical Sciences, Gulbarga, Karnataka **Assistant Professor, Department of Oral & Maxillofacial Surgery, Al-Badar Dental College & Hospital, Gulbarga, Karnataka ***HOD & Principal Department of Oral & Maxillofacial Surgery, Al – Ameen Dental College & Hospital, Bijapur, Karnataka ****Reader, ******Postgraduate Student, Department of Oral & Maxillofacial surgery, Al-Badar Dental College and Hospital, Gulbarga, Karnataka, India *****Assistant Professor, Department of Orthodontics, Al-Badar Deental College, Gulbarga, Karnataka, India. COMPARISON OF MIDAZOLAM WITH PROPOFOL AND PROPOFOL ALO N E I N M I N O R O RAL AN D M AXI LLO FACI AL SU RGI CAL PRO CED U RES Authors: Mohammad Ali R Patel*, Shereen Fatima**, Kenchappa Umesh Reddy***, Kiran Radder****, M. Arshad Hussain*****, Mohammed Haneef****** BUJOD BUJOD