LMRJ Volume 3 Issue 3 79 | Page Research article IMPACT OF MANDIBULAR RESECTION GUIDANCE PROSTHESES ON ORAL HEALTH RE- LATED QUALITY OF LIFE (OHRQoL) - A PROSPECTIVE STUDY S. Parithimar Kalaignan, Syed Ershad Ahmed 1 1 Department of Prosthodontics, Vinayaka Missions Sankarachariyar Dental College, Vinayaka Missions Research Foundation, Salem, Tamilnadu, India. ABSTRACT This prospective study was aimed to measure the impact of mandibu- lar resection guidance prostheses on oral health-related quality of life (OHRQol). A total of 35 patients with mandibulectomy defects were included. All the patients were rehabilitated with mandibular resec- tion guidance prostheses respectively. These patients were subjected for assessment of OHRQol. The assessment was done by using OHIP- Edent-19 and a novel scale—maxillofacial prosthesis performance scale (MFPPS). The assessment was done on all the patients at two weeks and three months of prosthesis function. The scores of OHIP- Edent, and MFPPS for mandibular resection guidance prostheses after two weeks were 33.20and 18.74 respectively. The scores of OHIP- Edent and MFPPS for mandibular resection guidance prostheses pros- theses at three months were 27.71and 15.20 respectively. These findings show significant improvements of prosthesis in terms of functional, physical, psychological and social parameters after long- term follow-up (3 months). Key Words: Maxillofacial Defects, Oral Health Impact Profile (OHIP), Intra- Oral Prostheses, Guide flange prostheses INTRODUCTION Maxillofacial defects result from both congenital and acquired causes leading to significant changes in the anatomic structures of the maxillofacial region 1, 2. Maxillofacial defects can be classified as maxillary defects and mandibular defects, both need surgical correction and rehabilitation with prostheses. Mandibulectomy involves extensive loss of tissues and associated functions resulting in an inability to masticate efficiently. Functional activities such as mastication, deglutition, phonetics, mandibular movements, control of saliva and psychic functioning are adversely affected post mandibulectomy 3 . The greatest challenges faced by max- illofacial Prosthodontist in rehabilitating these conditions include the rate of disease occurrence and financial constraints .They are frequently associated with Functional, Physical, Psychosocial and Esthetic Impair- ments 4. Brown‘s classification proposal depends upon the standard shape of the mandible having four corners: two vertical corners making the angles of the mandible, and two horizontal corners that are centred at the canine teeth on each side in the dentate mandible, and are roughly 7 mm anterior from the mental foramen in the edentulous jaw. Our proposed mandibular defect classification is logical and simple, and groups defects into categories that can be compared in an understandable way. The use of the corners of the mandible at the angles and the canine regions make this classification system a rational approach to categorise defects, in- creasing in size and complexity from class I (a simple lateral defect not including the condyle involving the angle or vertical corner) to class IV (which involves at least three corners) and class IVc (which includes total mandibulectomy). The proposed classification system shows the increase in morbidity in terms of aesthetics and function from class I to class IV. This morbidity is likely to increase with non-reconstructed cases in line Correspondence: Syed Ershad Ahmed Assistant Professor Department of Prosthodon- tics. Vinayaka Missions Sankara- chariyar Dental College, Vinayaka Missions Research Foundation Salem,Tamilnadu , India Email: drsyeder- shadahmed@vmsdc.edu.in DOI: 10.38106/LMRJ.2021.3.3-06 Received: 07.11.2020 Accepted: 25. 08..2021 Published: 30. 09.2021