_____________________________________________________________________________________________________ *Corresponding author: E-mail: otto.fustes@hc.ufpr.br; Asian Journal of Research and Reports in Neurology 4(1): 11-15, 2021; Article no.AJORRIN.64951 Cerebral Venous Thrombosis: Study of 12 Cases from Southern Brazil Otto Jesus Hernandez Fustes 1,2* , Carlos Arteaga Rodriguez 3 and Georgette Mouchaileh E. Ferreira 2 1 InNeuro, Curitiba, Brazil. 2 Neurology Service, Hospital das Nações, Curitiba, Brazil. 3 Positivo University, Medicine Department, Curitiba, Brazil. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information Editor(s): (1) Dr. Takashi Ikeno, National Center of Neurology and Psychiatry, Japan. Reviewers: (1) Belete Negese, Debre Berhan University, Ethiopia. (2) Mrs. Sarika Sukesh Nair, MGM New Bombay College of Nursing, India. Complete Peer review History: http://www.sdiarticle4.com/review-history/64951 Received 20 November 2020 Accepted 25 January 2021 Published 17 February 2021 ABSTRACT Cerebral venous thrombosis (CVT) is a pathology that affects the cerebral venous sinuses causing an ischemic and/or hemorrhagic brain, but, contrary to the arterial cerebral vascular accident, has a clinical presentation with varied signs and symptoms that are difficult to diagnose in the its initial phase. Objective: To present the clinical findings of twelve cases of CVT. Materials and methods: We reviewed the charts of patients admitted with a diagnosis of CVT. Results: We describe 8 females and 4 males, with mean age of 30 years. The most common signs and symptoms were: headache (89%), seizure (55.5%), cranial nerve palsy (44%) and hemiparesis (33%). All patients had diagnoses confirmed by nuclear magnetic resonance of the skull. The risk factors found were the use of oral and puerperium contraceptives. All patients were treated with oral anticoagulant, with no death reported in this series. Conclusion: Venous sinus thrombosis is an uncommon disease that requires a high index of suspected diagnosis by the medical team. The mortality rate is low and the treatment is usually effective. Short Communication