STUDIA UBB CHEMIA, LXV, 4, 2020 (p. 73-84) (RECOMMENDED CITATION) DOI:10.24193/subbchem.2020.4.06 COMPARATIVE FRAMEWORK OF CALCIUM PHOSPHATES-BASED PRODUCTS DERIVED FROM SUSTAINABLE MARINE AND TERRESTRIAL RESOURCES FOR BIOMEDICAL APPLICATIONS AURA-CĂTĂLINA MOCANU a , MARIAN MICULESCU a,* , ROBERT-CĂTĂLIN CIOCOIU a , TUDOR-MIHAI BUTTE a , ANA-IULIA BIȚĂ a , CLAUDIA-GEORGIANA MILEA a , AURORA ANTONIAC a , MARIUS VASILESCU a , OCTAVIAN TRANTE a , CIPRIAN POP a , LUCIAN-TOMA CIOCAN b ABSTRACT. Processing calcium and phosphor-rich natural resources, such as marble and seashells, and bovine and fish bones, envelops an environmentally friendly and eco-sustainable promising alternative for developing biomimetic products for various orthopaedic applications. In this regard, convenient, efficient, facile and completely reproducible technologies were involved in the fabrication process of biogenic calcium phosphates-based products through the conversion of the proposed resources. The aim of this research was to comparatively evaluate the morpho-compositional, structural and mechanical features of the developed products, subjected in advance to an air sintering program. The results revealed that the high temperature affects differently the morphological characteristics of the samples and facilitates the conservation of several elements, traced from their natural marine or terrestrial habitat. Moreover, the nature of the initial precursors clearly influenced the final composition of the samples: biphasic configuration for calcium carbonate derived products versus single phase for the calcium phosphate ones. The mechanical features are also a composed result of the resources type and sintering process, with significant recorded differences. Therefore, this study unveils the prospect for suitable strategies in terms of adequate natural precursor, fabrication technology and final properties of the biogenic products destined for a certain application in the biomedicine field. Keywords: marble, seashells, bovine bone, fish bone, biogenic hydroxyapatite, compact products, comparative assessment a University Politehnica of Bucharest, Department of Metallic Materials Science, Physical Metallurgy, 313 Splaiul Independentei, 060042, J Building, District 6, Bucharest, Romania. b „Carol Davila” University of Medicine and Pharmacy, Prosthetics Technology and Dental Materials Department, 37, Dionisie Lupu Street., District 1, 020022, Bucharest, Romania. * Corresponding author: marian.miculescu@upb.ro, m_miculescu@yahoo.com