Curr Trends Intern Med, an open access journal ISSN: 2638-003X 1 Volume 2; Issue 01 Current Trends in Internal Medicine Branton A, et al. Curr Trends Intern Med 2: 120. Research Article Complementary and Alternative Medicine: Effect of the Consciousness Energy Healing Treatment on Physicochemical Behaviour of Silver Sulfadiazine Alice Branton 1 , Mahendra Kumar Trivedi 1 , Dahryn Trivedi 1 , Gopal Nayak 1 , Snehasis Jana 2* 1 Trivedi Global, Inc., Henderson, USA 2 Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, India * Corresponding author: Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, India. Tel: +9102225811234; Email: publication@trivedisrl.com Citation: Branton A, Trivedi MK, Trivedi D, Nayak G, Jana S (2019) Complementary and Alternative Medicine: Effect of the Con- sciousness Energy Healing Treatment on Physicochemical Behaviour of Silver Sulfadiazine. Curr Trends Intern Med 2: 120. DOI: 10.29011/2638-003X.100020 Received Date: 7 January, 2019; Accepted Date: 1 February, 2019; Published Date: 11 February, 2019 DOI: 10.29011/2638-003X.100020 Abstract Silver sulfadiazine is a topical antibiotic used on burnt tissues to prevent infection. The aim of this study was to evaluate the impact of the Trivedi Effect ® -Consciousness Energy Healing Treatment on the physicochemical and thermal properties of silver sulfadiazine using PXRD, PSA, DSC, and TGA/DTG analysis. Silver sulfadiazine sample was divided into two parts. One part was considered as a control sample, which did not receive the Biofeld Energy Treatment. The second part received the Trivedi Effect ® -Consciousness Energy Healing Treatment remotely by a renowned Biofeld Energy Healer, Alice Branton, termed as the treated sample. The PXRD analysis exhibited that the peak intensities of the treated silver sulfadiazine were signifcantly decreased from 14.5% to 54.5% compared with the control sample. The crystallite sizes of the treated sample were signifcantly altered from -48.9% to 6.4% compared to the control sample. The average crystallite size of the Biofeld Energy Treated sample was found to be decreased by 13.99% as compared to the control sample. The particle sizes of the treated silver sulfadiazine were decreased signifcantly by 6.64% at d 10 followed by d 50 (-1.37%), d 90 (-0.55%) and D(4,3) (-2.44%) compared to the control sample. The specifc surface area of treated silver sulfadiazine was increased profoundly 11.23% compared to the control sample. The total weight loss was increased by 10.73%; whereas, the residue amount was decreased by 16.49% in the treated silver sulfadiazine compared with the control sample. Thus, the Trivedi Effect ® -Consciousness Energy Healing Treatment might lead to generate a new polymorphic form of silver sulfadiazine which would be more soluble, and bioavailable compared with the untreated sample. The Consciousness Energy Healing Treated silver sulfadiazine would be very useful to design more effcacious pharmaceutical formulations which might offer a better therapeutic response on the derma against bacteria and superfcial and partial thickness burn injuries. Keywords: Complementary and Alternative Medicine, Sil- ver sulfadiazine, Consciousness Energy Healing Treatment, The Trivedi Effect ® , PXRD, Particle size, DSC, TGA/DTG Introduction Silver sulfadiazine is a sulfonamide-based topical medicine having antibacterial and antifungal activity, act through a combined activity of silver and sulfadiazine [1]. Sodium chloride-containing body fuids interact with silver sulfadiazine, and silver ions are re- leased slowly into wounded areas. Silver ions catalyse the forma- tion of disulphide bonds leading to protein structural changes and inactivating thiol-containing enzymes [2]. Silver ions may also intercalate DNA thereby interfering with replication and transcrip- tion of bacteria. Sulfadiazine inhibits bacterial dihydropteroate synthase as an inhibitor of para-aminobenzoic acid, thereby result- ing in the disruption of folic acid metabolism and ultimately DNA synthesis [3,4]. Application to large areas or severe burns may lead to systemic absorption and lead to adverse effects similar to those of other sulphonamides [5]. Tentative evidence has found other antibiotics to be more effective in the healing of superfcial and partial thickness burn injuries; therefore, it is no longer generally recommended [6]. Study of the physicochemical properties of a pharmaceuti- cal product for its dissolution and absorption parameters are cru-