Journal of Food Science and Technology: ISSN-2384-5058, Vol. 5(3): pp 117-125, October, 2018.
Copyright © 2018. Spring Journals
Full Length Research
Evaluation of the Physicochemical and Thermal
Properties of Consciousness Energy Healing Treated
Polylactic-co-glycolic Acid (PLGA)
Gopal Nayak
1
, Mahendra Kumar Trivedi
1
, Alice Branton
1
, Dahryn Trivedi
1
, Snehasis Jana
2, *
1
Trivedi Global, Inc., Henderson, USA
2
Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, India
*Corresponding Author: Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, India. Tel: +91-022-25811234;
Email: publication@trivedieffect.com
Accepted 13
th
October, 2018.
Poly(lactic-co-glycolic acid) (PLGA) is an FDA approved popular biodegradable copolymer, which
has several applications in the pharmaceuticals and biomedical industries. But the degradation and
stability of PLGA is a major problem. The objective of this research work was to evaluate the effect
of the Trivedi Effect
®
-Consciousness Energy Healing Treatment on the physicochemical and thermal
properties of PLGA using modern analytical techniques. The test sample was divided into control
and treated parts. The control part of the test sample did not receive the Biofield Energy Treatment;
whereas the other part of the sample received the Biofield Energy Treatment remotely by a famous
Biofield Energy Healer, Gopal Nayak and was known as a treated sample. The particle size values
were significantly increased by 15.76% (d
10
), 15.73% (d
50
), 12.04% (d
90
), and 13.81% {D(4,3)}; hence,
the specific surface area was significantly decreased by 12.45% in the treated sample compared to
the control sample. The latent heat of evaporation and latent heat of fusion were altered by 1.05%
and -55.13%, respectively in the treated PLGA compared with the control sample. The total weight
loss was significantly increased by 10.34%; however, the residue amount was 95.77% less in the
treated PLGA sample compared to the control sample. From these results, it can be concluded that
the Trivedi Effect
®
-Consciousness Energy Healing Treated PLGA may show better flowability, shape,
and appearance compared with the control PLGA. The Biofield Energy Treated PLGA can provide
better benefits for designing the pharmaceutical/nutraceutical formulations and manufacturing of
biomedical devices, i.e., sutures, grafts, surgical sealant films, prosthetic devices, implants, micro,
and nanoparticles.
Keywords: PLGA, The Trivedi Effect
®
, Consciousness Energy Healing Treatment, Complementary and
Alternative Medicine, Particle size, Surface area, DSC, TGA/DTG
1. INTRODUCTION
Poly(lactic-co-glycolic acid) (PLGA) is a Food and Drug Administration (FDA) approved copolymer, which is
popular among the several available biodegradable polymers with long clinical experience (Makadia et al., 2011). This
copolymer is a synthesized from the polylactic acid and glycolic acid. On hydrolysis of its ester linkages releases the
monomers. The two monomers are the by-products of various metabolic pathways, therefore exhibit minimum
systemic toxicity in the body. Higher the content of glycolide units in the PLGA unit, lower the time required for
degradation. Thus, it has a great deal of attention in research and development due to its mechanical resistance,
constant biodegradation rate, and regular individual chain geometry (Erbettan et al., 2012). The PLGA is used for the
manufacturing of biomedical devices, i.e., prosthetic devices, grafts, sutures, surgical sealant films, implants, micro,
and nanoparticles (Pavot et al., 2014). It is amongst the FDA-approved polymers as a delivery vehicle for drugs,
proteins, and other macromolecules such as peptides, RNA, and DNA (Makadia et al., 2011). Explicitly, PLGA is useful