J Med Sci, Volume 54, Number 4, 2022 October: 315-330 315 *corresponding author: siti.nur.r@ugm.ac.id Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Volume 54, Number 4, 2022; 315-330 https://doi.org/10.19106/JMedSci005404202202 Submitted: 2021-12-29 Accepted : 2022-07-27 Keywords: vitamin D; serum 25(OH)D; obesity; deficiency; health workers Vitamin D levels of obesity and non-obesity health workers: a cross-sectional study in Dr. Sardjito General Hospital/Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada, Yogyakarta Siti Nur Rohmah 1 *, Dwita Dyah Adyarini 1 , Prenali Dwisthi Sattwika 1 , Anastasia Evi Handayaningsih 1 , Hemi Sinorita 2 , Vina Yanti Susanti 2 1 Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, 2 Endocrinology Metabolic Division, Department of Internal Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito General, Hospital, Yogyakarta, Indonesia ABSTRACT Obesity is one of the causes of chronic diseases, such as diabetes, hypertension, stroke, cancer, dyslipidemia, and heart disease. It is considered a financial burden on national health insurance since it drains the largest health fund. The study aimed to determine the difference in vitamin D levels in obese and non-obese health workers and analyze the factors that influence it. This was a cross-sectional study of the obese and non-obese health workers at Dr. Sardjito General Hospital, Yogyakarta. A total of 50 subjects, including 25 obese and 25 non-obese subjects were involved. Serum vitamin D levels was determined by ELISA. There was no significant difference between the obese and non- obese groups on vitamin D status (p<0.365). Vitamin D deficiency was found in 10% of subjects, whereas insufficient vitamin D levels were found in 46 and 44% of subjects, respectively. Vitamin D deficiency was more common in the obese (12%) than non-obese (8%) group. Contrarily, vitamin D insufficiency was more common in the non-obese (56%) than obese (36%) group. The serum vitamin D levels in the obese [30.08 (14.67-101.71) ng/mL] was not significantly different compare to those non-obese [28.54 (14.38-54.41) ng/mL] (p = 0.691). The multivariate analysis significantly showed that outdoor activities <30 min had a 7.061 times greater risk of having vitamin D deficiency/insufficiency compared to outdoor activities >30 min (OR 7.061; 95% CI: 1.064-46.872; p=0.043). In conclusion, there is no significant difference in vitamin D levels between the obese and non-obese groups. Vitamin D deficiency/insufficiency is more common in non-obese subjects than in obese subjects. Outdoor activity <30 min is a risk factor for vitamin D insufficiency/deficiency despite living in a tropical country with abundant sunlight throughout the year. ABSTRAK Obesitas merupakan salah satu penyebab penyakit kronis, seperti diabetes, hipertensi, stroke, kanker, dislipidemia, dan penyakit jantung. Obesitas dikhawatirkan menjadi beban jaminan kesehatan nasional karena menyedot dana kesehatan terbesar. Penelitian ini bertujuan untuk mengetahui perbedaan kadar vitamin D pada tenaga kesehatan dengan obesitas dan non obesitas serta menganalisis faktor-faktor yang mempengaruhinya. Penelitian potong lintang yang dilakukan pada tenaga kesehatan dengan obesitas dan non obesitas di RSUP Dr. Sardjito Yogyakarta. Total sampel penelitian ini adalah 50 subjek, meliputi 25 subjek obesitas dan 25 subjek non-obesitas. Kadar vitamin D serum diukur dengan metode ELISA. Tidak ada perbedaan nyata kadar vitamin D pada kelompok obesitas dan non obesitas (p<0,365). Defisiensi vitamin D ditemukan pada 10% subjek, sedangkan insufisiensi dan kecukupan vitamin D ditemukan pada 46% dan 44% subjek. Defisiensi vitamin D lebih